Royalty Report: Medical, Device, Diagnostic – Collection: 5266

$150.00

Curated Royalty Rate Report
Category: Technology Licenses, Created On: 2022-04-28, Record Count: 7

Description

This collection of transactions and supporting information was developed using our AI algorithm to curate similar royalty reports into a cohesive collection to support your licensing, transfer pricing or other transaction scenarios where documented royalty rates and/or deal terms are important.
Category: Technology Licenses
Created On: 2022-04-28
Record Count: 7

Primary Industries

  • Medical
  • Device
  • Diagnostic
  • Scientific & Technical Instruments
  • Dental
  • Surgical
  • Cancer

IPSCIO Report Record List

Below you will find the records curated into this collection.  This summary includes the complete licensed property description so that you can review and determine if this collection covers the topics, technology or transaction type that is relevant for your needs.  The full report will include all relevant deal data such as the royalty base, agreement date, term description, royalty rates and other deal terms.  For reference, here is a sample of a full IPSCIO curated royalty rate report: Sample Report

IPSCIO Record ID: 5266

License Grant
The Company agrees to sell, assign, transfer, set over and convey all rights, title and interest in and to said Original Agreement, including the exclusive licenses under U.S. Patent Nos. 4,284,895 and 4,437,006 in the Medical Field.  Patent Nos. 4,284,895 issued on August 18, 1981 relates to Method and apparatus for tomographic examination of an object by penetrating radiation and Patent Nos. 4,437,006 issued on March 13, 1984 relates to Method and apparatus for measuring radiation in computer-assisted tomography and radiographic applications.
License Property
Technology relates to the construction of an x-ray tomographic scanning prototype.

The Company has an exclusive license for the worldwide rights in the medical field to two patents for its proposed medical imaging camera. The two patents relate to high-speed single photon counting cameras and camera configurations which minimize the “noise” associated with the scattering of low energy photons.

IPSCIO Record ID: 6023

License Grant
The Licensor has granted the Licensee a non-exclusive worldwide license to use certain medical imaging technologies, known as Optical Coherence Tomography, or ‘OCT,’ in the field of general dentistry, excluding oral surgery and imaging through a microscope.
License Property
(a) Licensee’s Release of a Licensed Product;
(b) Licensee’s First Commercial Sale of a Licensed Product; or
(c) the second anniversary of the effective date.

Optical Coherence Tomography is a technique for obtaining sub-surface images of translucent or opaque materials at a resolution equivalent to a low-power microscope. It is effectively ‘optical ultrasound’, imaging reflections from within tissue to provide cross-sectional images.

There are many industrial, medical, and other applications where high resolution (generally less than 10 micrometer) images of, and measurements of distances, thicknesses, and optical properties of, a biological or other sample are required.

“Method And Apparatus For Optical Imaging With Means For Controlling The Longitudinal Range Of The Sample”  Issued US Patent 5,321,501, June 14, 1994. Filed 4/29/92. – A method and apparatus for performing optical imaging on a sample wherein longitudinal scanning or positioning in the sample is provided by either varying relative optical path lengths for an optical path leading to the sample and to a reference reflector, or by varying an optical characteristic of the output from an optical source applied to the apparatus. Transverse scanning in one or two dimensions is provided on the sample by providing controlled relative movement between the sample and a probe module in such direction and/or by steering optical radiation in the probe module to a selected transverse position. The probe module may be an external module or may be an endoscope or angioscope utilized for scanning internal channels. Multiple optical paths may be provided for parallel scanning and focus may be enhanced by varying the focal point in the sample in synchronism with longitudinal scanning of the sample.

“Method and Apparatus for Performing Optical Measurements” Issued US Patent 5,459,570, Oct. 14, 1995. Filed 3/16/93.

“Method and Apparatus for Performing Optical Imaging and Measurements” Issued in Europe and Japan.

“Method and Apparatus for Acquiring Images using a CCD Detector Array and No Transverse Scanner” Issued US Patent 5,465,147, Nov. 7, 1995. Filed 6/2/94. CIP of 4/29/91 filing.

“Method and Apparatus for Performing Optical Measurements using a Fiber Optic Imaging Guidewire, Catheter or Endoscope” Issued US Patent 6,134,003, Oct. 17, 2000. Filed 2/27/96.

“Methods and Apparatus for Forward-Directed Optical Scanning Instruments for the Acquisition of Optical Imaging and Delivery of Optical Radiation,” Pending Patent.

“Grating Based Phase Control Optical Delay Line” Issued US Patent 6,111,645 August, 2000.

“Method and Apparatus for Performing Optical Measurements using a Rapidly Frequency Tuned Laser” Issued US Patent 5,956,355 September 21, 1999.

“Short Coherence Length, Doppler Velocimetry System” Issued US Patent 5,501,226, 3/26/96. Filed 10/16/94. Issued EPO and Japan.

“Short Coherence Length, Doppler Velocimetry System” Issued US Patent 5,549,114, 8/27/96. Filed 10/23/95. Issued EPO and Japan.

“Optical Coherence Tomography Assisted Surgical Apparatus” Issued US Patent 6,004,314 December 21, 1999.

“OCT-Assisted Surgical Microscope with Multi- Coordinate Manipulator” Issued US Patent 5,795,295.

“Optical Coherence Tomography with New Interferometer” Issued US Patent 6,053,613.

“Method and Apparatus for Simultaneous Measuring the Length and Refractive Error of and Eye” Issued US Patent 5,975,699.

Measurement of Lens Characteristics” Issued US Patent 5,469,261 11/21/95.

“Fundus Illumination Apparatus Formed from Three Separated Radiation Path Systems” Issued US Patent 5,506,634, 4/9/96.

“Optical Coherence Tomography Corneal Mapping Apparatus” Issued US Patent 5,491,524, 2/13/96. Filed 10/5/94.

“Method and Apparatus for Optical Coherence Tomographic Fundus Imaging” Pending Patent.

“Gaze Tracking using Optical Coherence Tomography” Issued US Patent 5,644,642, 7/1/97. Filed 4/3/95.

“Optical Coherence Tomography Assisted Ophthalmologic Surgical Microscope” Issued US Patent 5,493,109, 2/20/96. Filed 8/18/94.

“Method and Apparatus for Optical Coherence Tomographic Fundus Imaging without Vignetting” Issued US Patent 5,537,162, 6/16/96. Filed 12/17/93.

“Method and Apparatus for High Speed Longitudinal Scanning in Imaging Systems” Issued US Patent 6,191,862 2/20/01.

“Fiber Optic Needle Probes for Optical Coherence Tomography Imaging” Patent Pending.

“Micro-Lens for Miniature Optical Probes” Patent Pending.

“Method and Apparatus for Performing Optical Frequency Domain Reflectometry” Issued US Patent 6,160,826. 12/12/00. Filed 1999.

“Broadband Light Source System and Method Thereof” Patent Pending.

“Apparatus and Method for Selective Data Collection and Signal to Noise Ratio Enhancement Using Optical Coherence Tomography” Patent Pending Filed 4/6/01.

“Fiber Optic Endoscopic Gastrointestinal Probe” Patent Pending.

IPSCIO Record ID: 26371

License Grant
The Company entered into an Exclusive License Agreement and a Sponsored Research Agreement in connection with the development of its second-generation OsteoSystem; worldwide rights, in the field of bone densitometry; patents claiming an invention in the field of quantitative radiographic imaging.
License Property
U.S. Patents No. 5,465,284 and 5,150,394 entitled System for Quantitative Radiographic Imaging
Field of Use
Field shall mean the area of bone densitometry.

IPSCIO Record ID: 236356

License Grant
Beginning in October 2003, the parties have been in discussions to resolve certain matters relating to the Agreement. This Amendment 2 is intended to fully resolve such matters.

The parties acknowledge that the non-exclusive license granted by Licensor to Licensee pursuant to Amendment 1 has been terminated by Licensee. Accordingly, Amendment 1 is hereby rescinded, except as stated.  With this amendment 2, the royalty has been updated.

License Property
With amendment 1, the patent identified is for Low Resistivity Photon-Transparent Window Attached to Photo-Sensitive Silicon Detector.
Field of Use
With amendment 1, Field of Use means the development, production and use of photodiodes within products to perform single photon nuclear medicine procedures.  Single photon, as used herein, means radioisotopes whose decay chain includes a primary gamma ray with energy greater than 50keV but does not include a positron emission tomography, the Non-exclusive Field of Use and all other kinds of x-ray imaging.

The Non-exclusive Field of Use means the development, production and use of photodiodes within products to perform x-ray computed tomography (CT) for medical imaging applications.  Non-Exclusive Field of Use specifically excludes the Field of Use, the use of positron emission tomography, as well as all kinds of x-ray imaging other than computed tomography for medical imaging applications.

IPSCIO Record ID: 233456

License Grant
The Parties are expanding the license to include a Non-Exclusive Field of Use.  With this amendment, the Agreement grant is replaced in its entirety with the following  The Licensor grants to a nontransferable, limited worldwide exclusive license, under Licensed Patents, only in the Field of Use, to develop, make, have made, use, practice, sell, have sold, and lease the Licensed Products.  And, a nontransferable, nonexclusive worldwide license, under Licensed Patents, only within the NonExclusive Field of Use, to develop, make, have made, use, practice, sell, and lease the Licensed Products.
License Property
With this amendment the patent identified is for Low Resistivity Photon-Transparent Window Attached to Photo-Sensitive Silicon Detector.
Field of Use
With this amendment, Field of Use means the development, production and use of photodiodes within products to perform single photon nuclear medicine procedures.  Single photon, as used herein, means radioisotopes whose decay chain includes a primary gamma ray with energy greater than 50keV but does not include a positron emission tomography, the Non-exclusive Field of Use and all other kinds of x-ray imaging.

The Non-exclusive Field of Use means the development, production and use of photodiodes within products to perform x-ray computed tomography (CT) for medical imaging applications.  Non-Exclusive Field of Use specifically excludes the Field of Use, the use of positron emission tomography, as well as all kinds of x-ray imaging other than computed tomography for medical imaging applications.

IPSCIO Record ID: 25927

License Grant
The University Foundation agrees to extend Licensee's right to exclusive, transferable worldwide, irrevocable licenses in foundation technology.  Terms and conditions of said licenses are set forth in the agreement entered into in 1992.
License Property
Foundation and Licensee previously entered into a Research Agreement for the development and commercialization of said technology dated June 1, 1992 and amended said agreement from time to time, the last amendment being August of 2001.

Medical Diagnostic Optical technology
1. #5,042,494, August 27, 1991, Method and Apparatus for Detecting Cancerous Tissue using Luminescence Excitation Spectra, R. R. Alfano.
2. #5,131,398, July 21, 1992, Method and Apparatus for Distinguishing Cancerous Tissue from Benign Tumor Tissue, Benign Tissue or Normal Tissue using Native Fluorescence, R. R. Alfano, B. Das, G. Tang.
3. #5,261,410, November 16, 1993, Method for determining if a Tissue is a Malignant Tumor Tissue, a Benign Tumor Tissue, or a Normal Benign Tissue using Raman Spectroscopy, R. R. Alfano, C.-H. Liu, W. S. Glassman.
4. #5,293,872, March 15, 1994, Method for Distinguishing between Calcified Atherosclerotic Tissue and Fibrous Atherosclerotic Tissue or Normal Cardiovascular Tissue Using Raman Spectroscopy, R. R. Alfano, C. H. Liu
5. #5,348,018, September 20, 1994, Method for determining if Tissue is Malignant as opposed to Non-Malignant using Time-Resolved Fluorescence Spectroscopy, R. R. Alfano, A. Pradhan, G. C. Tang, L. Wang, Y. Budansky, B. B. Das.
6. #5,413,108, May 9, 1995, Method and Apparatus for Mapping a Tissue Sample for and Distinguishing Different Regions thereof based on Luminescence Measurements of Cancer-indicative Native Fluorophor, R. R. Alfano.
7. #5,467,767, November 21, 1995, Method for Determining if Tissue is Malignant as opposed to Non-Malignant using Time-resolved Fluorescence Spectroscopy, R. R. Alfano, Asima Pradhan, G. C. Tang, L. Wang, Y. Budansky, B. B. Das.
8. #5,635,402, June 3, 1997. Technique for Determining whether a Cell is Malignant as opposed to Non-malignant using Extrinsic Fluorescence Spectroscopy, R. R. Alfano, Cheng H. Liu, Wei L. Sha, Yury Budansky.
9. #5,769,081, June 23, 1998, Method for Detecting Cancerous Tissue using Optical Spectroscopy and Fourier Analysis, R. R. Alfano, A. Katz, Y. Yang.
10. #5,849,595, December 15, 1998, Method for Monitoring the Effects of Chemotherapeutic Agents on Neoplasmic Media, R. R. Alfano, G. C. Tang, S. P. Schantz.
11. #5,983,125, November 9, 1999, Method and apparatus for in vivo examination of subcutaneous tissues inside an organ of a body using optical spectroscopy, R. R. Alfano, Y. Budansky.
12. #6,006,001, December 21, 1999, Fiber optic assembly useful in optical spectroscopy, R. R. Alfano, S. Demos, G. Zhang.
13. #6,080,584, June 27, 2000, Method and apparatus for detecting the presence of cancerous and precancerous cells in a smear using native fluorescence spectroscopy, Robert R. Alfano, Singaravelu Ganesan, and Yury Budansky.
14. #6,091,985, July 18, 2000, Detection of cancer and precancerous conditions in tissues and/or cells using native fluorescence excitation spectroscopy, Robert R. Alfano, Singaravelu Ganesan, Alvin Katz, Yang Yuanlong.

Optical Imaging for Medical Purposes
1. #5,371,368, December 6, 1994, Ultrafast Optical Imaging of Objects in a Scattering Medium, R. R. Alfano, P. P. Ho, L. Wang.
2. #5,625,458, April 29, 1997, Method and System for Imaging Objects in Turbid Media using Diffusive Fermat Photons, R. R. Alfano, A. Y. Polishchuk.
3. #5,644,429, July 1, 1997 (see #5,371,368), 2-Dimensional Imaging of Translucent Objects in Turbid Media, R. R. Alfano, P. P. Ho, X. Liang.
4. #5,710,429, January 20, 1998, Ultrafast Optical Imaging of objects in or Behind Scattering Media, R. R. Alfano, Feng Liu, Q. Z. Wang P. Ho, L. M. Wang, X. Liang.
5. #5,719,399, February 17, 1998, Imaging and Characterization of Tissue based upon the Preservation of Polarized Light transmitted therethrough, R. R. Alfano, S. G. Demos.
6. #5,799,656, September 1, 1998, Optical Imaging of Breast Tissues to enable the Detection therein of Calcification Regions Suggestive of Cancer, R. R. Alfano, P. P. Ho, L. Wang, X. Liang, P. Galland.
7. #5,813,988, September 29, 1998, Time Resolved Diffusion Tomographic Imaging in Highly Scattering Turbid Media, R. R. Alfano, W. Cai, F. Liu, M. Lax, Bidyut B. Das.
8. #5,847,394, December 8, 1998, Imaging of Objects Based upon the Polarization or Depolarization of Light, R. R. Alfano, S. G. Demos.
9. #5,931,789, August 3, 1999, Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media, Robert R. Alfano, Wei Cai, Feng Liu, Melvin Lax.
10. # 6,208,886 B1, March 27, 2001, Non-linear optical tomography of turbid media, Robert R. Alfano, Yici Guo, Feng Liu, Ping Pei Ho.
11. # 6,215,587, April 10, 2001, Microscope imaging inside highly scattering media, Robert R. Alfano, Gordon Anderson, Feng Liu.

Field of Use
Patent relates to cancer detection apparatus using visible luminescence.

IPSCIO Record ID: 6021

License Grant
The University has granted the Licensee an exclusive license for patents and patent applications in the field of Optical Coherence Imaging technology for dental applications in humans and animals, in the United States. The Licensor also grants to Licensee the right to issue royalty-bearing subLicenses to third parties in the Field of Use.
License Property
United States Patents Granted

5,570,182 Method for Detection of Dental Caries and Periodontal Disease Usin Optical
6,179,611 Dental Optical Coherence Domain Reflectometry Explorer

Optical Coherence Tomography, or ‘OCT’, is a technique for obtaining sub-surface images of translucent or opaque materials at a resolution equivalent to a low-power microscope. It is effectively ‘optical ultrasound’, imaging reflections from within tissue to provide cross-sectional images.

Field of Use
The field of Optical Coherence Imaging technology for dental applications in humans and animals.
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