Royalty Report: Medical, Device, Catheter – Collection: 51408

License Grant

Pursuant to the License Agreement, the Licensor granted the company the exclusive world-wide rights to develop, manufacture and distribute the SCMS.  The License Agreement requires the company to use commercially reasonable efforts to develop and market the SCMS within certain timeframes, subject to specified exceptions.

License Property

Scivanta Cardiac Monitoring System (the SCMS), a minimally invasive two-balloon esophageal catheter system used to monitor cardiac performance.

Field of Use

This agreement pertains to the medical industry.

License Grant

The Licensor granted the Licensee the exclusive world-wide rights to develop, manufacture and distribute the SCMS, a minimally invasive two-balloon esophageal catheter system used to monitor cardiac performance.

License Property

Tangible Property
1. One prototype two-balloon esophogeal catheter.
2. One prototype system control box.
3. One copy of Source Code.
4. One laptop with operational Source Code, which will be returned to Licensor within ninety (90) days of the transfer, unless otherwise mutually agreed to by the parties.
5. One Dynamap Blood Pressure Monitor, which will be returned to Licensor within ninety (90) days of the transfer, unless otherwise mutually agreed to by the parties.
6. One ECG device compatible with the system, which will be returned to Licensor within ninety (90) days of the transfer, unless otherwise mutually agreed to by the parties.

5,048,532 U.S. Patent Method and Apparatus for Measuring Blood Pressure (S-409)

5,181,517 U.S. Continuation in Part Patent Method and Apparatus for the Measurement of Atrial Pressure (S-409)

5,263,485 U.S. Continuation in Part Patent Combination Esophageal Catheter for the Measurement of Atrial Pressure (S-409

6,120,442 U.S. Patent Method and Apparatus for Noninvasive Determination of Cardiac Performance Parameters (R-5421)

5,697,375 U.S. Continuation in Part Patent Method and Apparatus Utilizing Heart Sounds for Determining Pressure Associated with the Left Atrium (S-409)

License Grant

The Licensor granted the Company the exclusive world-wide rights to develop, make and sell the HCMS, a minimally invasive two-balloon esophageal catheter system used to monitor cardiac performance.

License Property

The HCMS will provide the primary measures of cardiac performance and left atrial pressure which are crucial measurements in treating critically ill patients.

5,048,532-Method and Apparatus for Measuring Blood Pressure (S-409)
5,181,517-Method and Apparatus for the Measurement of Atrial Pressure (S-409)

License Grant

This license is granted upon execution of the option to license and already accepted by Licensee. With Licensee exercising the option to license, Licensee is additionally granted  a non-exclusive, sublicensable license in the field for the countries Licensor is not able to fulfill Sections 3.8 or 3.9 to use any Background Patents necessary for the use and exploitation of the Catheter Technology, Peripheral Technology or Product to the extent related to the Application.

License Property

Licensor is a leading company developing, manufacturing and selling devices as well as developing treatment plans for various medical indications, such as deep brain stimulation or cardiac ablation.

Product shall mean and comprise a combination of hardware, software and workflow procedures allowing the performance of the Application or parts thereof under simultaneous MR imaging, which the Parties wish to develop under this Agreement and which is defined in more detail in Agreement. The Product shall be integrated and developed by Licensor as a medical product according to applicable local medical product regulations including, but not limited to the EU and the USA, integrating and combining the Software, MR System, Catheter Technology and Peripheral Technology. The summary describes the components and operation of an MRI-guided EP ablation system. The system uses active (signal receiving) invasive devices and special software for customized image reconstruction and display. In the prototyping phase, the software component of the system will run on a computer attached to the scanner, while for the product version, the software component of the system will run on the scanners host computer.

MR System shall mean any applicable Licensee MR system. Target MR System for the Product include the Magnetom Verio and the Magnetom Espree. Other MR System might be added after mutual agreement. The MR System is currently provided by Licensee as a medical product according to applicable local medical product regulations in several countries, including, but not limited to, the EU, Canada and the USA.

Software means software and dedicated MR sequences, which are developed by Licensee according to requirement specifications by Licensor. These specifications are defined in the Agreement. For the avoidance of doubt, Software does not include the base modules IFE and IRTTT, or any further developments or future versions of IFE or IRTTT, but only the dedicated plug in module dedicated to the workflow of the Product developed under this Agreement.

Background Patents shall mean patent applications, patents, utility models and other statutory protection with regard to MR System, Application, Catheter Technology, Peripheral Technology, Software, Integration or the Product under which one PARTY is the owner and/or has the right of determination at any time during the term of this Agreement and which are not a Development Result.

Catheter Technology shall mean and comprise the invasive medical devices (e.g. guidewire, catheters) supplied by Licensor for the use in the Product and within and in close proximity to an MR System and which are defined in this Agreement. The Catheter Technology shall be provided by Licensor as a medical product according to applicable local medical product regulations including, but not limited to, the EU and the USA.

Peripheral Technology means hardware and software required by the user to perform the Application with the Product and which is not already included in Catheter Technology or Software or MR System.

Application shall mean the treatment of cardiac arrhythmia by catheter mediated ablation under simultaneous MR imaging and catheter mediated cardiac electrophysiological mapping under simultaneous MR imaging by using the Product. In the event the width of an Application is specified through guidelines of regulatory bodies like SFDA, CE, FDA, such specification shall apply.

Field of Use

Licensee is a leading company in developing, manufacturing and selling Magnetic Resonance (“MR”) Imaging systems, which are used worldwide for diagnostics of a wide variety of medical indications. MR imaging is free of ionizing radiation and is therefore well-suited for continued supervision of treatment procedures.

The Parties wish to establish a Cooperation and Development Agreement aiming at a combination of the capabilities of Catheter Ablation and MR imaging in developing a product combination that allows performing the treatment of cardiac arrhythmias by catheter mediated ablation and catheter mediated cardiac electrophysiological mapping procedure under simultaneous MR imaging for worldwide marketing and sales.  The Parties agree that this treatment consists of a procedure with the involvement of different medical devices, including catheters and mapping technology as well as MR imaging guidance. The Parties intend to develop an MR workflow with all required components integrated into the special requirements of the MR environment.

Field shall mean treatment of cardiac arrhythmia by catheter mediated ablation under simultaneous MR imaging and catheter mediated cardiac electrophysiological mapping under simultaneous MR imaging.

License Grant

University hereby grants to each Canadian Licensee a worldwide non-exclusive, royalty-bearing right and license, with the right to sublicense, under the Penn Know-How to make, have made, use, distribute, sell, offer for sale, develop, promote, import, export and otherwise exploit Licensed Products in the Field of Use during the Term (the “License”).

License Property

Licensed Product means any Product relating to mitral valves and made, used or sold by utilizing or practicing Licensor Know-How,  including the “Tiara” transcatheter mitral valve product and any other next generation of “Tiara” product.  Tiaraâ„¢ is a minimally invasive transcatheter device for patients who experience severe mitral regurgitation utilizing the Licensor know-how.

“Licensed Product” means any Product (i) relating to mitral valves and (ii) made, used or sold by utilizing or practicing Penn Know-How.

Field of Use

The Licensee is a medical device company that specializes in developing, manufacturing, and marketing cardiovascular products including Tiara. Tiara is implanted in the heart using a minimally invasive, transapical transcatheter approach without the need for open-heart surgery or use of a cardiac bypass machine.