Royalty Report: Medical, Device, Diagnostic – Collection: 4853


Curated Royalty Rate Report
Category: Technology Licenses, Created On: 2022-04-28, Record Count: 14


This collection of transactions and supporting information was developed using our AI algorithm to curate similar royalty reports into a cohesive collection to support your licensing, transfer pricing or other transaction scenarios where documented royalty rates and/or deal terms are important.
Category: Technology Licenses
Created On: 2022-04-28
Record Count: 14

Primary Industries

  • Medical
  • Device
  • Diagnostic
  • Scientific & Technical Instruments
  • Dental
  • Cancer
  • Surgical
  • Semiconductors
  • RAM
  • Test/Monitoring
  • Ultrasound
  • Personal Care Products

IPSCIO Report Record List

Below you will find the records curated into this collection.  This summary includes the complete licensed property description so that you can review and determine if this collection covers the topics, technology or transaction type that is relevant for your needs.  The full report will include all relevant deal data such as the royalty base, agreement date, term description, royalty rates and other deal terms.  For reference, here is a sample of a full IPSCIO curated royalty rate report: Sample Report

IPSCIO Record ID: 4853

License Grant
Licensor, an individual, hereby grants and Licensee hereby accepts an exclusive irrevocable license for use of the Technology in the human and veterinary medical fields, to produce, have produced, manufacture, have manufactured for it, to use and/or sell Patented Products to any distributor, reseller or end user (i.e., physicians, veterinarians, hospitals, clinics, universities or any other user), either separately or in combination with other products, and to use the Technology and Licensor Know-How in the specified fields, with the right to sublicense its Subsidiaries.
License Property
Licensor has invented, developed and filed patent applications relating to certain electronic endoscopes, flexible optical catheters, complementary viewing systems, and related disposable products for use in connection with detection, diagnosis and treatment of disease or injury in humans and animals.

1. OPTICAL CATHETER. All methods, apparatus, claims and products relating to certain products, processes and techniques described for use in and for a system consisting of a small diameter endoscope comprise of a sterilizable optical catheter which carries a coherent fiber-optic bundle capable of transmitting an image, and parallel fiber-optic bundles capable of transmitting light, which is coupled to an apparatus consisting of an eyepiece and/or console containing light source(s), camera(s) and viewing screen(s), as described in that certain patent application (No. 018,630) filed by Licensor with the U.S. Patent Office on February 25, 1987 (the 'Patent Application').

FLUORESCENCE DETECTION. A methodology of fluorescence detection allowing for the visualization of light emitting compounds from biological tissues and certain treatment applications thereon, using the Optical Catheter.
The optical catheter and fluorescence detection system includes, but is not limited to, the following
Endoscope with removable eyepiece, #018630
Optical catheter, ## 1,194,849 and 4,417,710
Laser endoscope, #4,589,404
Laser illuminator, #4,011,403
Steerable sheath for use with selected removable optical catheter, #5,325,845
Imaging tissue or stone removal basket, #5,311,858
Method and system for embollizing blood vessels, #4,869,246
Deflectable sheath for optical catheter, #07,581,592
Deformable and removable sheath for optical catheter, #07,581,591

2. THE ADAIR/VERESS NEEDLE. This device allows the introduction of gas, instruments, viewing devices and catheters into body cavities, particularly the abdominal cavity (peritoneum) including (but not limited to) the following
Gas insufflation needle with instrument port, #4,869,717

3. ELECTRONIC VIDEO LAPAROSCOPE. (a) All rigid video endoscopes with sterilizable sheath (all angles of view); (b) video endoscope with operative channels; thoracic endoscopes (rigid and deflectable); (c) 3-D technology on all endoscopes; sterile sheaths on all rigid endoscope products; and (d) all patents pending related to 'flipping of chip and bump bonding' for use in all endoscopic applications; all of which, (being described in clauses (a), (b), (c), and (d) above, including (but not limited to) the following
Rigid video endoscope with sterilizable sheath, #4,878,485, reissue #33,845
Heat sterilizable electronic video laparoscope, #5,188,094 Stereoscopic endoscope, #5,381,784
Operative electronic video laparoscope, subsequently abandoned
Miniaturized electronic imaging chip, #07,954,550, subsequently abandoned, continuation in part, #08,155,996

Field of Use
The term 'veterinary medical field' shall mean the field of veterinary applications and uses of the Technology to nonhuman animals including mammalian animals, and for the maintenance or improvement of health and/or growth or for the diagnosis, alleviation or cure of disease.

IPSCIO Record ID: 1878

License Grant
The Company acquired the Rotatable Chip technology in 1993 via a nonexclusive license agreement, expiring June 30, 2009.
License Property
The Rotatable Chip technology  relates to U.S. Patent No. 4,858,001 entitled Modular Endoscopic Apparatus With Image Rotation.

Complementary Metal Oxide Sensor (CMOS) imaging chip being developed for disposable electronic endoscopes or cameras for the medical and dental markets.

Field of Use
Field of Use Medical and dental cameras and endoscopes.

IPSCIO Record ID: 4716

License Grant
The Licensee acquired a patented technology for direct viewing of induced tissue fluorescence by a human viewer through an endoscope.  The Technology is covered by United States patent number 6,110,106.

IPSCIO Record ID: 6023

License Grant
The Licensor has granted the Licensee a non-exclusive worldwide license to use certain medical imaging technologies, known as Optical Coherence Tomography, or ‘OCT,’ in the field of general dentistry, excluding oral surgery and imaging through a microscope.
License Property
(a) Licensee’s Release of a Licensed Product;
(b) Licensee’s First Commercial Sale of a Licensed Product; or
(c) the second anniversary of the effective date.

Optical Coherence Tomography is a technique for obtaining sub-surface images of translucent or opaque materials at a resolution equivalent to a low-power microscope. It is effectively ‘optical ultrasound’, imaging reflections from within tissue to provide cross-sectional images.

There are many industrial, medical, and other applications where high resolution (generally less than 10 micrometer) images of, and measurements of distances, thicknesses, and optical properties of, a biological or other sample are required.

“Method And Apparatus For Optical Imaging With Means For Controlling The Longitudinal Range Of The Sample”  Issued US Patent 5,321,501, June 14, 1994. Filed 4/29/92. – A method and apparatus for performing optical imaging on a sample wherein longitudinal scanning or positioning in the sample is provided by either varying relative optical path lengths for an optical path leading to the sample and to a reference reflector, or by varying an optical characteristic of the output from an optical source applied to the apparatus. Transverse scanning in one or two dimensions is provided on the sample by providing controlled relative movement between the sample and a probe module in such direction and/or by steering optical radiation in the probe module to a selected transverse position. The probe module may be an external module or may be an endoscope or angioscope utilized for scanning internal channels. Multiple optical paths may be provided for parallel scanning and focus may be enhanced by varying the focal point in the sample in synchronism with longitudinal scanning of the sample.

“Method and Apparatus for Performing Optical Measurements” Issued US Patent 5,459,570, Oct. 14, 1995. Filed 3/16/93.

“Method and Apparatus for Performing Optical Imaging and Measurements” Issued in Europe and Japan.

“Method and Apparatus for Acquiring Images using a CCD Detector Array and No Transverse Scanner” Issued US Patent 5,465,147, Nov. 7, 1995. Filed 6/2/94. CIP of 4/29/91 filing.

“Method and Apparatus for Performing Optical Measurements using a Fiber Optic Imaging Guidewire, Catheter or Endoscope” Issued US Patent 6,134,003, Oct. 17, 2000. Filed 2/27/96.

“Methods and Apparatus for Forward-Directed Optical Scanning Instruments for the Acquisition of Optical Imaging and Delivery of Optical Radiation,” Pending Patent.

“Grating Based Phase Control Optical Delay Line” Issued US Patent 6,111,645 August, 2000.

“Method and Apparatus for Performing Optical Measurements using a Rapidly Frequency Tuned Laser” Issued US Patent 5,956,355 September 21, 1999.

“Short Coherence Length, Doppler Velocimetry System” Issued US Patent 5,501,226, 3/26/96. Filed 10/16/94. Issued EPO and Japan.

“Short Coherence Length, Doppler Velocimetry System” Issued US Patent 5,549,114, 8/27/96. Filed 10/23/95. Issued EPO and Japan.

“Optical Coherence Tomography Assisted Surgical Apparatus” Issued US Patent 6,004,314 December 21, 1999.

“OCT-Assisted Surgical Microscope with Multi- Coordinate Manipulator” Issued US Patent 5,795,295.

“Optical Coherence Tomography with New Interferometer” Issued US Patent 6,053,613.

“Method and Apparatus for Simultaneous Measuring the Length and Refractive Error of and Eye” Issued US Patent 5,975,699.

Measurement of Lens Characteristics” Issued US Patent 5,469,261 11/21/95.

“Fundus Illumination Apparatus Formed from Three Separated Radiation Path Systems” Issued US Patent 5,506,634, 4/9/96.

“Optical Coherence Tomography Corneal Mapping Apparatus” Issued US Patent 5,491,524, 2/13/96. Filed 10/5/94.

“Method and Apparatus for Optical Coherence Tomographic Fundus Imaging” Pending Patent.

“Gaze Tracking using Optical Coherence Tomography” Issued US Patent 5,644,642, 7/1/97. Filed 4/3/95.

“Optical Coherence Tomography Assisted Ophthalmologic Surgical Microscope” Issued US Patent 5,493,109, 2/20/96. Filed 8/18/94.

“Method and Apparatus for Optical Coherence Tomographic Fundus Imaging without Vignetting” Issued US Patent 5,537,162, 6/16/96. Filed 12/17/93.

“Method and Apparatus for High Speed Longitudinal Scanning in Imaging Systems” Issued US Patent 6,191,862 2/20/01.

“Fiber Optic Needle Probes for Optical Coherence Tomography Imaging” Patent Pending.

“Micro-Lens for Miniature Optical Probes” Patent Pending.

“Method and Apparatus for Performing Optical Frequency Domain Reflectometry” Issued US Patent 6,160,826. 12/12/00. Filed 1999.

“Broadband Light Source System and Method Thereof” Patent Pending.

“Apparatus and Method for Selective Data Collection and Signal to Noise Ratio Enhancement Using Optical Coherence Tomography” Patent Pending Filed 4/6/01.

“Fiber Optic Endoscopic Gastrointestinal Probe” Patent Pending.

IPSCIO Record ID: 28487

License Grant
The Licensor granted the Licensee a non-exclusive license agreement for the use of the patent rights and technology as they relate to cervical and ovarian cancer.
License Property
The Company agreed to settle an arbitration proceeding instituted by anther party against the Company through the transfer to the other party of certain patents, patent applications and other intellectual property rights relating to the AcCell technology.

The AcCell product is a computer-aided automated microscopy instrument designed to help medical specialists examine and diagnose specimens of human cells.

U.S. Patent 6,535,626; 6,430,309; 6,285,498; 6,148,096; 6,151,161; 6,118,581; 6,091,842; 6,081,740; 5,999,844; 5,963,368; 5,930,732; 5,833,794; 5,690,892; 5,077,806; 5,073,857

Field of Use
Licensed Field shall mean the field of products designed, developed, tested, manufactured, distributed, marketed, approved, sold, provided, and/or used exclusively for the screening of cervical or ovarian cancer which require the incorporation of  a fluorescent probe as its primary probe,  or which may incorporate other fluorescent or non-fluorescent probes, and in which the assay itself (a procedure employing one or more reagents which determines the biological state of a clinical specimen comprised of cells or tissues) is primarily fluorescent.

Licensee have designed and manufactured the AcCell(TM) computer-aided automated microscopy instrument and the AcCell Savant(TM), an instrument that includes an AcCell instrument and software and which collects quantitative cellular information used in support of a diagnostic process.

Licensee is a life sciences company engaged in the design, development and commercialization of cost-effective screening systems to assist in the early detection of cancer.

IPSCIO Record ID: 401

License Grant
The Company hereby grants to Licensee an exclusive, non-transferable non-divisible license to make, have made, use, offer to sell and sell Licensed Products covered by the U.S. Patents and Foreign Patents for use in cervical and ovarian gynecological applications for Point of Care and concurrent with a patient’s medical office visit in a physician’s office and the non-exclusive license to make, have made, use, offer to sell and sell Licensed Products covered by the U.S. Patents and Foreign Patents for use in cervical and ovarian gynecological applications for Point of Care in labs outside of the physician's office.
License Property
U.S. Patents means (i) AccuMed’s Patent entitled A Method and Apparatus For Imaging and Sampling Diseased Tissue Using Autofluorescence U.S. patent number 5,999,844 dated 12/07/99; (ii) the continuations, continuations-in-part or divisions thereof, if any; and (iii) any and all improvements, modifications, extensions, renewals or reissues of such Patent, if any.
Field of Use
This License Agreement is with respect to U.S. Patents and Foreign Patents rights for use in cervical and ovarian gynecological applications.

IPSCIO Record ID: 28959

License Grant
This agreement entitles the Company to sales of the MedCam Pro and MedCam Pro Plus products.
License Property
The MEDCAM is an economic, color, 1/4' single chip CCD imaging product that yields 270k pixel resolution. It has a c-mount lens and comes with a variety of adapters for microscopes. Standard cable length is 8' and also has a 20' long extension cable for remoting images to a monitor or recording device. The camera has an electronic iris and one lux sensitivity. The MedCam is also available in a 1/2' chip version called the MEDCAM PRO.

The MEDCAM PRO PLUS (non-soakable/soakable) is a bundled package featuring the MedCam Pro integrated into a 'one-button' on/off halogen fiber optic light source and includes the necessary fiber optic cables. The light source includes an S-VHS or a composite video output. The MedCam Pro Plus also includes the Company's proprietary 'universal' endocoupler that is designed to accept nearly all of the surgical endoscopes on the market.

The MEDCAM PRO is a new self-contained endoscopic video camera/light source utilizing cutting edge, self-contained camera technology.

Field of Use
This agreement pertains to the hardware and software videoconferencing solution industry.

IPSCIO Record ID: 2126

License Grant
The Company hereby grants to Licensee an exclusive, non-transferable, non-divisible license to make, have, made, use, offer to sell, and sell Licensed Products covered by the Claims of the Patents throughout the Territory on the terms and provisions hereof.
License Property
U.S. Patents means (i) the Application for Letters Patent identified as Case No. 96,242 titled A Method and Apparatus for Imaging and Sampling Diseased Tissue Using Autofluorescence as filed under United States Patent Application Serial No. 08/845,261 on April 23, 1997, (ii) Case No. 96,242-A, which is a continuation in part thereof, as filed under United States Patent Application Serial No. 08/951,018 on October 15, 1997.
Field of Use
The rights granted apply to diseased tissues.

IPSCIO Record ID: 6021

License Grant
The University has granted the Licensee an exclusive license for patents and patent applications in the field of Optical Coherence Imaging technology for dental applications in humans and animals, in the United States. The Licensor also grants to Licensee the right to issue royalty-bearing subLicenses to third parties in the Field of Use.
License Property
United States Patents Granted

5,570,182 Method for Detection of Dental Caries and Periodontal Disease Usin Optical
6,179,611 Dental Optical Coherence Domain Reflectometry Explorer

Optical Coherence Tomography, or ‘OCT’, is a technique for obtaining sub-surface images of translucent or opaque materials at a resolution equivalent to a low-power microscope. It is effectively ‘optical ultrasound’, imaging reflections from within tissue to provide cross-sectional images.

Field of Use
The field of Optical Coherence Imaging technology for dental applications in humans and animals.

IPSCIO Record ID: 203978

License Grant
The Canadian Licensor grants to Licensee an exclusive, worldwide license, with the right to grant and authorize sublicenses, to Licensors entire interest in and to the Licensed Patents within the Field to make, have made, use, import, have imported, sell, offer for sale and otherwise exploit and distribute Licensed Products within the Field, and practice any method, process or procedure included within the Licensed Patents in the Field.
License Property
The licensed patents are for Two-Dimensional and Three-Dimensional Digital Ultrasound Tracking Systems for surgery.  The Licensed Product means a product within the scope of one or more Valid Claims of the Licensed Patents in the country of manufacture or sale;  produced, processed or otherwise manufactured by a process or method within the scope of one or more Valid Claims of the Licensed Patents in the country of such manufacture; or; used in a process and/or method within the scope of one or more Valid Claims of the Licensed Patents in the country where such product is made or sold.
Field of Use
The Field shall mean use of any medical device and procedure applications in and on the heart that utilize essentially real-time triangulation algorithms to determine the three-dimensional position of transducers, excluding procedures solely and directly related to heart valve surgery.

IPSCIO Record ID: 27725

License Grant
The Japanese Licensor grants to Licensee the non-exclusive license to develop, manufacture, sell and have sold the Licensee Products incorporating Licensor's Technology in Non-Pacific Rim Territories for the Medical Diagnostics Field.
License Property
Chip means a substrate which contains a grating pursuant to the Grating SPR Technology and is coated with a conductive surface.

Flow Cell means a device which allows liquids to flow through it and consist of a Chip and has an optically clear cover slip which is attached to the Chip by a means that allows for fluid flow there through.

Grating SPR Technology means the use of thin conductive films on a surface or surfaces of a grating or other diffracting substrate to conduct chemical analysis.

PATENT NO.                          TITLE                        JAPANESE PATENT NO.
  US 4,931,384           Optical Assay Technique (Merlin I)             JP 1903195
  US 5,118,608           Optical Assay Technique (Merlin I)             JP 2502222
  US 4,882,288           Assay Technique and Equipment                  JP 1928364
                         (Merlin II)
  US 4,992,385           Polymer-Coated Optical Structures              JP 2528134
                         and Methods of Making and Using                JP 2592588
                         the Same (Cellulose Nitrate Films)

  US 4,828,387           Film Measuring Device and Method               JP 2511057
                         with Internal Calibration to
                         Minimize the Effect of Sample
                         Movement (Calibration Notches)
  US 5,310,686           Polymer-Coated Optical Structures              JP 2710243
                         (Sensor Using Photoresist)
  CA 1,302,875           (Waveguide Sensor)                             JP 2572829
  US 6,093,536           (Enhanced SPR Assay)                           JP 2073383

Field of Use
This agreement pertains to the medical diagnostics field.  Medical Diagnostics Field means those fields, the applications and products which under current laws and regulations of the United States would require approval of the United States Food and Drug Administration if the application or product incorporating the application were sold for clinical use in the United States.

IPSCIO Record ID: 3088

License Grant
Licensor has been granted a License from the University with respect to UMBC Know-how and UMBC Patent Rights pursuant to the terms and conditions of two License Agreements between UMBC and Licensor which, contemplates the Licensor granting subLicenses. The Licensor is granting a worldwide, subLicense to Licensee, to use the UMBC Know-how and UMBC Patent Rights in connection with the Licensee's development, manufacture, production, distribution, sale, export and import of commercial products within the Licensed Field.
License Property
Bioreactor Vessels shall mean a line of bioreactor vessels, culture bags or other incubator systems vessels, including either one, two, or three sensor patches produced by UMBC, Licensor, Licensee or other parties, including gamma sterilized vessels, for use with the Licensee's equipment and accessories.

UMBC Ref. 2343GR Bioreactor and Bioprocessing Technique US Patent No.6,673,532 issued 1/6/2004
EPO Patent Application S/N 01961662.2 filed August 14, 2001 Canada Patent Application S/N 2,429,474 filed August 14, 2001
US Patent No. 7,041,493 issued May 9, 2006
UMBC Ref. 2385GR Ratiometric Fluorescence pH Sensor for Non-Invasive Monitoring US Patent Application No. 10/609,720, filed June 30, 2003;
Publication No. 2005-0090014 UMBC Ref. 2441IK Ion-Sensitive Fluorescence Optical Sensor US Patent No. 7,029,630 issued April 18, 2006 UMBC Ref.
No 2396GR Device and Method for On-line Non-Invasive Measurement of Cell Mass in Culture Vessels US Patent Application No. 60/374,593, filed April 22, 2002
UMBC Ref. No. 2391GR High-Stability, Non-Invasive Autoclavable Naked Optical CO2 Sensors
UMBC Ref. No. 2405GR Wireless/Remote Fluid Addition Module

Field of Use
Licensed Field shall mean all possible applications using incubator systems for Bioreactor Vessels, in volumes of two hundred fifty milliliters or more but not greater than five liters.

IPSCIO Record ID: 27222

License Grant
The Licensor granted the Licensee a non-exclusive sublicense in the field of hair removal under the MGH patents.  Patented invention pertaining to the use of lasers for hair removal; LightSheer diode laser system (Patent No.  5,595,568).
License Property
United States Patent No. 5,595,568  (Permanent Hair Removal Using Optical Pulses).
Field of Use
The rights granted apply to hair removal.

IPSCIO Record ID: 203456

License Grant
Attached to this settlement agreement, the Licensor grants a worldwide non-exclusive license under Licensors Patent Rights and Know-how to make, have made for it, use, and sell Licensed Products. The license granted herein is expressly limited to the specific Licensed Products defined herein, and does not include the right to sublicense except to an Affiliate.

This license granted for Laser Angioplasty Catheters is non-cancelable by Licensee during the period from the Effective Date through June 30, 2009.

This license granted for Non-Laser Functioning Catheters and Guidewires for use with Licensees Laser Therapy Systems is non-exclusive.

License Property
The licensors patents include, but are not limited to, Method of Improving the Biocompatibility of Solid Surfaces, Surface Coating Agents and Substrate Surface Preparation.

The Licensed Products means Medical Products that are surface-treated with photoreactive polyvinylpyrrolidone copolymer, non-photoreactive polyvinylpyrrolidone, photoreactive polyacrylamide copolymer, one or more of the photoreactive crosslinking agents known to the parties as PR01 and PR04, a compound for promoting polymer-to-metal adhesion known to the parties as TL03, or any combination of these compounds, for the purpose of providing a lubricious surface to the Medical Products.

MEDICAL PRODUCTS-B1 Laser Angioplasty Catheters
The Medical Products means excimer laser angioplasty catheters specifically adapted for coronary and peripheral use. Medical Products includes Licensees chronic total occlusion laser angioplasty catheters.

MEDICAL PRODUCTS-B2 Non-Laser Functioning Catheters and Guidewires for use with Spectranetics Laser Therapy Systems
The Medical Products means the following Licensee-labeled non-laser functioning catheters and guidewires for Licensees laser therapy system that are specifically designed and labeled for use solely with laser angioplasty catheters (I) BIAS sheath, (ii) support catheters, (iii) cardiac lead locking device, and (iv) chronic total occlusion steerwires.  Medical Products does not include catheters for (I) infusion of diagnostic, therapeutic, or embolic agents in the neurovascular region, or (ii) insertion of therapeutic embolic devices in the neurovascular region. Medical Products does not include catheters used to deliver stents of any type.

Field of Use
Licensee designs, manufactures, markets and distributes single-use medical devices used in minimally invasive surgical procedures within the vascular system in conjunction with our proprietary excimer laser system.
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