Category: Technology Licenses
Created On: 2022-04-28
Record Count: 7
- Technical Know How
IPSCIO Report Record List
Below you will find the records curated into this collection. This summary includes the complete licensed property description so that you can review and determine if this collection covers the topics, technology or transaction type that is relevant for your needs. The full report will include all relevant deal data such as the royalty base, agreement date, term description, royalty rates and other deal terms. For reference, here is a sample of a full IPSCIO curated royalty rate report: Sample Report
IPSCIO Record ID: 316774
The SIS ECM biomaterial used in the medical device products are manufactured by Licensor. CanGaroo is soft and pliable and is designed to conform to the implantable device for easy handling and implantation. The SIS ECM is designed to mitigate the biologic foreign body response that normally occurs around the electronic device.
The CanGaroo envelope is constructed from perforated, multi-laminate sheets of decellularized, non-crosslinked, lyophilized small intestine submucosa (SIS) extracellular matrix (ECM), derived from porcine small intestinal submucosa, a natural biomaterial, which is rich in natural growth factors, structural proteins and collagens.
CanGaroo was designed to mitigate complications deriving from implantable electronic devices and the shortcomings of synthetic envelopes. We believe that CanGaroo is the only biological product that forms a natural, systemically vascularized pocket that conforms to and securely holds implantable electronic devices. CanGaroo is cleared for use with pacemaker pulse generators, defibrillators and other cardiac implantable electronic devices as well as vagus nerve stimulators, spinal cord neuromodulators, deep brain stimulators and sacral nerve stimulators.
IPSCIO Record ID: 317633
The product portfolio addresses a broad spectrum of spine surgery procedures and consists of innovative spinal fixation systems (implantable hardware systems that are mechanically attached to the spine and provide stability), interbody implants (devices implanted between the vertebral bodies of the spine), surgical instruments (instruments used to prepare the spine and implant our devices) and biologics (allograft or synthetic biomaterials intended to augment or replace the normal capacity of such tissue in the body).
â€œProduct Lineâ€ shall mean each of the following product categories, with each understood to specifically contain and be solely composed of the individual products and parts set forth on Schedule A (i) Mosaic, (ii) Vertu, (iii) Lucent Lateral, (iv) Lucent Expandable, (v) ISP (Clutch), and (vi) Zip Tie (Karma).
The Company is a medical device company focused on the design, development and commercialization of a comprehensive portfolio of systems, products and technologies for spine surgery procedures, with a strategic focus on minimally invasive surgery (â€œMISâ€) procedures.
IPSCIO Record ID: 353931
Sub-licensor is engaged in the research, development, manufacture and marketing of perfusion decellularization and recellularization technology and the products that are created utilizing such technology.
Decellularization. The anatomical structure of organs is highly complex and enormously challenging to reproduce synthetically. We utilize porcine organs as the scaffold for creating human organs because significant anatomical and vascular similarities exist between the two speciesâ€™ scaffolding. Using our proprietary perfusion decellularization process we remove the porcine cells from harvested porcine organs leaving behind a scaffold of extracellular matrix (â€œECMâ€) that retains the architecture, mechanical properties, and vascular network of the original organ structure. Porcine ECM is estimated to be over 93% homologous to human ECM which significantly reduces potential for antibody formation and adverse reaction. In addition, we have generated human clinical data demonstrating the safety of our decellularized porcine liver scaffold in clinical trials of two products we previously developed, commercialized and spun out, MiromeshÂ® and MirodermÂ®.
Recellularization. Recellularization is the process of growing new functional organs starting with the ECM that remains after the decellularization process is completed. We currently use living human cells harvested from organ donors to re-seed the ECM, and in the future intend to develop new techniques using patient-derived stem cells. Living human cells are adaptive, and when introduced into the decellularized ECM display unique regenerative, plasticity, and adhesion properties. The process of recellularization occurs in a bioreactor where media and living human cells are perfused into the ECM in the appropriate sequence in order to facilitate cellular regeneration and organ functionality.
IPSCIO Record ID: 191026
U.S. provisional patent application no. 60/612,018 – Tissue expanders and methods of use
One method of correcting skin deficit is to stimulate creation of new skin. Implantation of a device that expands and stretches the existing skin causes a growth response in which new skin is created. While the exact physiologic mechanism of this response is not fully understood, clinical success has been reported for many years.
One aspect of the disclosure is a tissue expansion system, including an implantable device adapted to be implanted within a patient, wherein the implantable device has an anterior portion, a posterior portion, an inferior portion, and a superior portion, and wherein the implantable device comprises a communication component secured in the superior and anterior portions, and an external device adapted to be disposed external to the patient to wirelessly communicate with the communication component to control the expansion of the implantable device.
IPSCIO Record ID: 289542
6,970,742 – Method for detecting, diagnosing, and treating cardiovascular disease
6,328,699 – Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure
IPSCIO Record ID: 88532
8,954,148 Key Fob controller for an implantable neurostimulator
8,483,836 Automated search to identify a location for electrical stimulation to treat a patient
8,515,545 Current steering neurostimulator device with unidirectional current sources
8,571,667 Active current control using the enclosure of an implanted pulse generator
8,738,153 Implantable lead with braided conductors
8,757,485 System and method for using clinician programmer and clinician programming data for inventory and manufacturing prediction and control
8,761,892 Active current control using the enclosure of an implanted pulse generator
8,761,897 Method and system of graphical representation of lead connector block and implantable pulse generators on a clinician programmer
8,781,592 Identifying an area for electrical stimulation to treat a patient
8,812,125 Systems and methods for the identification and association of medical devices
8,868,199 System and method of compressing medical maps for pulse generator or database storage
8,874,219 Arbitrary waveform generator and neural stimulation application
8,903,496 Clinician programming system and method
8,983,616 Method and system for associating patient records with pulse generators
8,996,115 Charge balancing for arbitrary waveform generator and neural stimulation application
8,996,117 Arbitrary waveform generator and neural stimulation application with scalable waveform feature
8,700,175 Devices and methods for visually indicating the alignment of a transcutaneous energy transfer device over an implanted medical device
9,002,466 Diversity antennas for neurostimulator programming devices
9,031,664 Current steering neurostimulator device with unidirectional current sources
9,031,666 Devices and methods for visually indicating the alignment of a transcutaneous energy transfer device over an implanted medical device
9,067,074 Automated search to identify a location for electrical stimulation to treat a patient
9,072,903 System and method of establishing a protocol for providing electrical stimulation with a stimulation system to treat a patient
9,098,610 Communication for implantable medical devices
9,101,767 Measuring load impedance with active stimulation pulses in an mplanted pulse generator
9,126,043 Patient handheld device for use with a spinal cord stimulation system
D663,035 Two-port implantable medical device
D665,086 Three-port implantable medical device
D665,087 Multi-port implantable medical device
D671,900 Pocket controller for implantable neurostimulator
D698,779 Clinician programmer for implantable neurostimulator
IPSCIO Record ID: 375
Licensor owns a patent relating to Neurocyberenetic Prosthesis Technology (U.S. Patent No. 4,702,254) and other pending patent applications and know-how, and technology relating thereto (collectively referred to as the â€œTechnologyâ€).
Oct. 27, 1987
Sept. 19, 1989
JuneÂ 25, 1991
MarchÂ 3, 1989
SeptemberÂ 12, 1989
SeptemberÂ 5, 1990
Austria, Belgium, Switzerland, Germany, France, United
Kingdom, Liechtenstein, Luxembourg, Netherlands, Sweden
SeptemberÂ 11, 1984