Royalty Report: Medical, Supply, Surgical – Collection: 3101


Curated Royalty Rate Report
Category: Technology Licenses, Created On: 2022-04-28, Record Count: 10


This collection of transactions and supporting information was developed using our AI algorithm to curate similar royalty reports into a cohesive collection to support your licensing, transfer pricing or other transaction scenarios where documented royalty rates and/or deal terms are important.
Category: Technology Licenses
Created On: 2022-04-28
Record Count: 10

Primary Industries

  • Medical
  • Supply
  • Surgical
  • Tissue
  • Drugs
  • Wound Care
  • Pharmaceuticals

IPSCIO Report Record List

Below you will find the records curated into this collection.  This summary includes the complete licensed property description so that you can review and determine if this collection covers the topics, technology or transaction type that is relevant for your needs.  The full report will include all relevant deal data such as the royalty base, agreement date, term description, royalty rates and other deal terms.  For reference, here is a sample of a full IPSCIO curated royalty rate report: Sample Report

IPSCIO Record ID: 3101

License Grant
The Licensee has entered into multiple license agreements with three Universities.  Under the terms of the License Agreements, the Licensee acquired exclusive worldwide licenses for underlying technology used in repairing and regenerating nerves.

The licensed technologies include the rights to issued patents and patents pending in the United States and international markets.

License Property
Avance® Nerve Graft is a human tissue for transplantation.  Avance® Nerve Graft is processed nerve allograft (human) intended for the surgical repair of peripheral nerve discontinuities to support regeneration across the defect.

The AxoGuard® Nerve Protector is indicated for the repair of peripheral nerve injuries where there is no gap. The device is supplied sterile and is intended for one-time use.

Field of Use
The Licnesee is a regenerative medicine company with a portfolio of proprietary products and technologies for peripheral nerve reconstruction and regeneration.

In order to improve surgical reconstruction and regeneration of peripheral nerves, the Licensee has developed and licensed technologies, which are used in its products. Its product portfolio includes Avance® Nerve Graft which the Licensee believes is the first and only commercially available allograft nerve for bridging nerve discontinuities (a gap created when the nerve is severed) AxoGuard® Nerve Connector, a coaptation aid allowing for close approximation of severed nerves, and AxoGuard® Nerve Protector, an implant that protects nerves during the body's healing process after surgery.

IPSCIO Record ID: 27054

License Grant
This license agreement with Licensor grants the Company an exclusive worldwide license in exchange for a royalty.

The Company has research and license agreements with Licensor pursuant to which Licensor was sponsored by the Company to conduct research in certain fields of nerve regeneration, repair, recovery and/or maintenance of nerve function in an effort to develop and produce new products for potential pharmaceutical and other commercial applications.

License Property
The Adcon family of medical devices are being developed by the Company to inhibit excess scarring and adhesion formation at the surgical site. The initial Adcon products are formulated as proprietary resorbable gels for direct application by surgeons to organs and tissues during surgery to inhibit surgical scarring and adhesions. Adcon-L is designed to inhibit scarring and adhesions formation following lumbar disc surgery.
Field of Use
Adcon-T/N is designed for use in tendon and peripheral nerve repair surgeries, such as carpal tunnel syndrome and tenolysis.

IPSCIO Record ID: 2357

License Grant
Licensor and Licensee have  entered into agreement relating to certain technology.
License Property
'Licensed Products' shall mean any product, good, or item within the Field, produced in whole or in part, using a part or all of the technology embodied in Licensed Patents, and made of, but not limited to, Fluorinated Hydrocarbons (including, but not limited to, PTFE, ePTFE, FEP, PFA, HFP and VF).

A. Soft Tissue Includes Gore patch products used in the following applications
i)  Reconstruction of hernias and soft tissue deficiencies, such as abdominal wall defects, diaphragmatic hernia, laparoscopic hernia, pelvic floor and lid reconstruction, ventral hernia, laparoscopic inguinal hernia, muscle flap reconstruction, vaginal prolapse, rectal prolapse, scrotal hernia, gastric banding and temporary facial bridging; and
ii)  Plastic and reconstructive surgery, such as malarplasty, mentoplasty, rhinoplasty, maxilloplasty, frontal defects, reconstructive lip augmentations, orbital repair, facial folds, facial slings and auricuoplasty.

B. Cardiovascular Includes Gore patch products used in cardiovascular and cardiac patching, such as carotid patch, angioplasty, profundaplasty, AV access graft patching, septal defects, outflow tracts, aneurysm repair and other patch angioplasty.

C. Surgical Membrane/Adhesion Limiting Includes Gore patch products used in the following applications
i)   Reconstruction or repair of the peritoneum, where minimal adhesions to a prosthetic material are desired, such as infertility surgery, gynecological surgery and gynecological and surgical oncology;
ii)  Temporary or permanent prosthesis for the repair of dura mater during neurosurgery, such as tumor resection, tethered cord releases, trauma repair and Chiari decompression;
iii) Reconstruction of the pericardium where minimal adhesions are desired; and
iv)  Wrap for pedicled arterial conduits.

IPSCIO Record ID: 237258

License Grant
The University grants to Licensee
—   an exclusive license, limited to the Licensed Field and the Licensed Territory, under the Licensed Patents to make, have made, use and sell, offer to sell, have sold and import Licensed Products and/or Licensed Processes;
—   a non-exclusive license, limited to the Licensed Field and the Licensed Territory under the Licensed Know-How to make, have made, use and sell, offer to sell, have sold and import Licensed Products and/or Licensed Processes.

Licensee may grant written, exclusive or nonexclusive Sublicenses to third parties.

License Property
The patents are for Materials and Methods for Nerve Repair, and, Materials and Methods for Nerve Grafting, and, Materials and Methods for Nerve Grafting, Selection of Nerve Grafts, And In Vitro Nerve Tissue Culture.
Field of Use
The Licensed Field shall be limited to the field of medical devices, human therapeutics and human and animal tissue.

IPSCIO Record ID: 27346

License Grant
Biograft peripheral vascular graft; Biograft is used to bypass occluded blood vessels and is produced from modified human umbilical veins; for use in lower limb vascular reconstructions when a saphenous vein is not available.

IPSCIO Record ID: 27294

License Grant
The Company has acquired from an undisclosed Licensor the product licenses and product manufacturing rights to Peri-Guard Processed Bovine Pericardium.
License Property
The products are used in a wide variety of surgical procedures, designed to reinforce, reconstruct and repair tissue and prevent leaks of air, blood and other body fluids.

IPSCIO Record ID: 283919

License Grant
The Agreement provides the Company a license to patent rights and other intellectual property related to New Zealand Licensor's products and technologies for use in certain indications.  This License provides for the exclusive supply of ovine rumen and manufacture of Licensee OviTex and OviTex PRS products.
License Property
Licensors Product consist of but not limited to Ovine rumen, the forestomach of a sheep.  It is the source of the biologic material used in our products. In manufacturing our products, Licensee uses biologic material from ovine rumen because of its plentiful supply, optimal biomechanical profile and open collagen architecture that allows for rapid cellular infiltration.

Through this License, Licensee intellectual property broadly covers the development of extracellular matrix scaffolds derived from ovine rumen and methods for isolating these scaffolds from ovine rumen.

OviTex Reinforced Tissue Matrix, or OviTex, addresses unmet needs in hernia repair and abdominal wall reconstruction by combining the benefits of biologic matrices and polymer materials. OviTex PRS, addresses unmet needs in plastic and reconstructive surgery.

OviTex PRS is indicated for use in implantation to reinforce soft tissue where weakness exists in patients requiring soft tissue repair or reinforcement in plastic and reconstructive surgery.

Field of Use
OviTex Reinforced BioScaffolds (RBSs) are intended for use as a surgical mesh to reinforce and/or repair soft tissue where weakness exists. Indications for use include the repair of hernias and/or abdominal wall defects that require the use of reinforcing or bridging material to obtain the desired surgical outcome.

Licensee is a commercial stage medical technology company focused on designing, developing and marketing a new category of tissue reinforcement materials to address unmet needs in soft tissue reconstruction. Licensee offer a portfolio of advanced reinforced tissue matrices that improve clinical outcomes and reduce overall costs of care in hernia repair, abdominal wall reconstruction and plastic and reconstructive surgery. Licensee products are an innovative solution that integrate multiple layers of minimally-processed biologic material with interwoven polymers in a unique embroidered pattern, which we refer to as a reinforced tissue matrix.

IPSCIO Record ID: 369277

License Grant
Licensor, an university division of public health sciences, hereby grants to Licensee and Licensee accepts from Licensor, an exclusive, worldwide right and license, including the right to sublicense, to make, use and sell the Improvement Products under Licensors rights in the Improvement Patents in the Licensed Field only.

Licensor hereby grants to Licensee and Licensee accepts from Licensor, a non-exclusive, worldwide, right and license, including the right to sublicense, to the Know-How.

Licensor hereby grants to Licensee and Licensee accepts from Licensor for the Option Period (in each case) a non-transferable (except as specifically stated in Agreement), exclusive option to negotiate in good faith for a royalty-bearing, worldwide, exclusive license, including the right to sublicense, to practice all the rights under the New Development Patents in the Licensed Field only (the Option).

License Property
Patent Rights
6,673,339 – Prosthetic kidney and its use for treating kidney disease
6,576,019 – Bladder reconstruction
6,514,292 – Corporal tissue penile reconstruction
Field of Use
The agreement is in the field of regenerative medicine that will advance the development of organs and tissues to treat human diseases and disabilities.

The primary focus of the research will be on creating “neo-organs” and tissues. Neo-organs and tissues are derived from a patient’s own cells that are grown on a scaffold or model that is bioresorbable, or can be absorbed by the body. These neo-organs become functional replacements after being implanted in the patient’s body. Since they come from a patient’s own cells (autologous cells) there is virtually no risk of rejection from the body’s immune system.
In tissue engineering, neo-organ is a final structure of procedure based on transplantation of constructs consisting of endogenous stem/progenitor cells grown ex vivo within predesigned matrix scaffolds. The scaffold eventually is resorbed, leaving transplanted cells and the stroma that they produce in the body.

Licensed Field means human and animal organs, tissues and tissue-engineered and regenerative medicine products directed to their functions in the following areas (i) Genitourinary Tissue, (ii) Kidney Tissue, (iii) Cardiovascular Tissue, (iv) Nervous Tissue, and (v) Trachea Tissue. Each of Genitourinary Tissue, Kidney Tissue, Cardiovascular Tissue and Nervous Tissue is a Subfield.

Genitourinary Tissue means the reproductive system and the urinary system, including the male and female internal and external genitalia as well as all organs concerned in the formation and voidance of urine, but excluding Kidney Tissue. For the removal of doubt, Genitourinary Tissue is not to be considered Cardiovascular Tissue merely because it contains components of Cardiovascular Tissue.

Kidney Tissue means the kidney.

Cardiovascular Tissue means arteries, arterial tissue, veins and venous tissue. Cardiovascular Tissue does not include cardiac muscle tissue or heart valves.

Nervous Tissue means the (i) central nervous system, (ii) peripheral nervous system, and (iii) functional subcomponents and subunits of (i) and (ii) above. For the removal of doubt, a tissue or organ is not considered Nervous Tissue merely because it contains components of Nervous Tissue.

Trachea Tissue means the trachea and functional subcomponents and subunits thereof. Trachea Tissue does not include the bronchus and larynx.

IPSCIO Record ID: 7167

License Grant
The Licensee entered into a License Agreement with a University Licensor to in-License certain technology and intellectual property relating to engineered biological nerve grafts.

The Licensee received the exclusive worldwide rights to commercialize products comprising this technology for all fields of use.

IPSCIO Record ID: 288845

License Grant
The Licensor, a wholly owned subsidiary of an Israeli University and the Licensee agree that this Agreement shall supersede the License Agreement which is hereby terminated and shall have no further force and effect.   The original agreement was an exclusive worldwide license in Licensors patents and know-how to develop and commercialize products based on or incorporating coral-based conditioned medium for neuronal tissue regeneration and/or repair.
License Property
The services agreements related to laboratory access and other services.
Field of Use
The Field of Use shall mean treatments of traumatic brain injuries.

The Licensee received an exclusive worldwide royalty-bearing license in Licensor's patents and know-how to develop and commercialize products for neuronal tissue regeneration and/or repair, resulting from Licensor's research or technology or the Licensee's research funding.

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