Royalty Report: Medical, Device, Diagnostic – Collection: 28959

License Grant

This agreement entitles the Company to sales of the MedCam Pro and MedCam Pro Plus products.

License Property

The MEDCAM is an economic, color, 1/4' single chip CCD imaging product that yields 270k pixel resolution. It has a c-mount lens and comes with a variety of adapters for microscopes. Standard cable length is 8' and also has a 20' long extension cable for remoting images to a monitor or recording device. The camera has an electronic iris and one lux sensitivity. The MedCam is also available in a 1/2' chip version called the MEDCAM PRO.

The MEDCAM PRO PLUS (non-soakable/soakable) is a bundled package featuring the MedCam Pro integrated into a 'one-button' on/off halogen fiber optic light source and includes the necessary fiber optic cables. The light source includes an S-VHS or a composite video output. The MedCam Pro Plus also includes the Company's proprietary 'universal' endocoupler that is designed to accept nearly all of the surgical endoscopes on the market.

The MEDCAM PRO is a new self-contained endoscopic video camera/light source utilizing cutting edge, self-contained camera technology.

Field of Use

This agreement pertains to the hardware and software videoconferencing solution industry.

License Grant

Licensor, an individual, hereby grants and Licensee hereby accepts an exclusive irrevocable license for use of the Technology in the human and veterinary medical fields, to produce, have produced, manufacture, have manufactured for it, to use and/or sell Patented Products to any distributor, reseller or end user (i.e., physicians, veterinarians, hospitals, clinics, universities or any other user), either separately or in combination with other products, and to use the Technology and Licensor Know-How in the specified fields, with the right to sublicense its Subsidiaries.

License Property

Licensor has invented, developed and filed patent applications relating to certain electronic endoscopes, flexible optical catheters, complementary viewing systems, and related disposable products for use in connection with detection, diagnosis and treatment of disease or injury in humans and animals.

1. OPTICAL CATHETER. All methods, apparatus, claims and products relating to certain products, processes and techniques described for use in and for a system consisting of a small diameter endoscope comprise of a sterilizable optical catheter which carries a coherent fiber-optic bundle capable of transmitting an image, and parallel fiber-optic bundles capable of transmitting light, which is coupled to an apparatus consisting of an eyepiece and/or console containing light source(s), camera(s) and viewing screen(s), as described in that certain patent application (No. 018,630) filed by Licensor with the U.S. Patent Office on February 25, 1987 (the 'Patent Application').

FLUORESCENCE DETECTION. A methodology of fluorescence detection allowing for the visualization of light emitting compounds from biological tissues and certain treatment applications thereon, using the Optical Catheter.
The optical catheter and fluorescence detection system includes, but is not limited to, the following
Endoscope with removable eyepiece, #018630
Optical catheter, ## 1,194,849 and 4,417,710
Laser endoscope, #4,589,404
Laser illuminator, #4,011,403
Steerable sheath for use with selected removable optical catheter, #5,325,845
Imaging tissue or stone removal basket, #5,311,858
Method and system for embollizing blood vessels, #4,869,246
Deflectable sheath for optical catheter, #07,581,592
Deformable and removable sheath for optical catheter, #07,581,591

2. THE ADAIR/VERESS NEEDLE. This device allows the introduction of gas, instruments, viewing devices and catheters into body cavities, particularly the abdominal cavity (peritoneum) including (but not limited to) the following
Gas insufflation needle with instrument port, #4,869,717

3. ELECTRONIC VIDEO LAPAROSCOPE. (a) All rigid video endoscopes with sterilizable sheath (all angles of view); (b) video endoscope with operative channels; thoracic endoscopes (rigid and deflectable); (c) 3-D technology on all endoscopes; sterile sheaths on all rigid endoscope products; and (d) all patents pending related to 'flipping of chip and bump bonding' for use in all endoscopic applications; all of which, (being described in clauses (a), (b), (c), and (d) above, including (but not limited to) the following
Rigid video endoscope with sterilizable sheath, #4,878,485, reissue #33,845
Heat sterilizable electronic video laparoscope, #5,188,094 Stereoscopic endoscope, #5,381,784
Operative electronic video laparoscope, subsequently abandoned
Miniaturized electronic imaging chip, #07,954,550, subsequently abandoned, continuation in part, #08,155,996

Field of Use

The term 'veterinary medical field' shall mean the field of veterinary applications and uses of the Technology to nonhuman animals including mammalian animals, and for the maintenance or improvement of health and/or growth or for the diagnosis, alleviation or cure of disease.

License Grant

The Company acquired the Rotatable Chip technology in 1993 via a nonexclusive license agreement, expiring June 30, 2009.

License Property

The Rotatable Chip technology  relates to U.S. Patent No. 4,858,001 entitled Modular Endoscopic Apparatus With Image Rotation.

Complementary Metal Oxide Sensor (CMOS) imaging chip being developed for disposable electronic endoscopes or cameras for the medical and dental markets.

Field of Use

Field of Use Medical and dental cameras and endoscopes.

License Grant

The Licensor has granted the Licensee a non-exclusive worldwide license to use certain medical imaging technologies, known as Optical Coherence Tomography, or ‘OCT,’ in the field of general dentistry, excluding oral surgery and imaging through a microscope.

License Property

(a) Licensee’s Release of a Licensed Product;
(b) Licensee’s First Commercial Sale of a Licensed Product; or
(c) the second anniversary of the effective date.

Optical Coherence Tomography is a technique for obtaining sub-surface images of translucent or opaque materials at a resolution equivalent to a low-power microscope. It is effectively ‘optical ultrasound’, imaging reflections from within tissue to provide cross-sectional images.

There are many industrial, medical, and other applications where high resolution (generally less than 10 micrometer) images of, and measurements of distances, thicknesses, and optical properties of, a biological or other sample are required.

“Method And Apparatus For Optical Imaging With Means For Controlling The Longitudinal Range Of The Sample”  Issued US Patent 5,321,501, June 14, 1994. Filed 4/29/92. – A method and apparatus for performing optical imaging on a sample wherein longitudinal scanning or positioning in the sample is provided by either varying relative optical path lengths for an optical path leading to the sample and to a reference reflector, or by varying an optical characteristic of the output from an optical source applied to the apparatus. Transverse scanning in one or two dimensions is provided on the sample by providing controlled relative movement between the sample and a probe module in such direction and/or by steering optical radiation in the probe module to a selected transverse position. The probe module may be an external module or may be an endoscope or angioscope utilized for scanning internal channels. Multiple optical paths may be provided for parallel scanning and focus may be enhanced by varying the focal point in the sample in synchronism with longitudinal scanning of the sample.

“Method and Apparatus for Performing Optical Measurements” Issued US Patent 5,459,570, Oct. 14, 1995. Filed 3/16/93.

“Method and Apparatus for Performing Optical Imaging and Measurements” Issued in Europe and Japan.

“Method and Apparatus for Acquiring Images using a CCD Detector Array and No Transverse Scanner” Issued US Patent 5,465,147, Nov. 7, 1995. Filed 6/2/94. CIP of 4/29/91 filing.

“Method and Apparatus for Performing Optical Measurements using a Fiber Optic Imaging Guidewire, Catheter or Endoscope” Issued US Patent 6,134,003, Oct. 17, 2000. Filed 2/27/96.

“Methods and Apparatus for Forward-Directed Optical Scanning Instruments for the Acquisition of Optical Imaging and Delivery of Optical Radiation,” Pending Patent.

“Grating Based Phase Control Optical Delay Line” Issued US Patent 6,111,645 August, 2000.

“Method and Apparatus for Performing Optical Measurements using a Rapidly Frequency Tuned Laser” Issued US Patent 5,956,355 September 21, 1999.

“Short Coherence Length, Doppler Velocimetry System” Issued US Patent 5,501,226, 3/26/96. Filed 10/16/94. Issued EPO and Japan.

“Short Coherence Length, Doppler Velocimetry System” Issued US Patent 5,549,114, 8/27/96. Filed 10/23/95. Issued EPO and Japan.

“Optical Coherence Tomography Assisted Surgical Apparatus” Issued US Patent 6,004,314 December 21, 1999.

“OCT-Assisted Surgical Microscope with Multi- Coordinate Manipulator” Issued US Patent 5,795,295.

“Optical Coherence Tomography with New Interferometer” Issued US Patent 6,053,613.

“Method and Apparatus for Simultaneous Measuring the Length and Refractive Error of and Eye” Issued US Patent 5,975,699.

Measurement of Lens Characteristics” Issued US Patent 5,469,261 11/21/95.

“Fundus Illumination Apparatus Formed from Three Separated Radiation Path Systems” Issued US Patent 5,506,634, 4/9/96.

“Optical Coherence Tomography Corneal Mapping Apparatus” Issued US Patent 5,491,524, 2/13/96. Filed 10/5/94.

“Method and Apparatus for Optical Coherence Tomographic Fundus Imaging” Pending Patent.

“Gaze Tracking using Optical Coherence Tomography” Issued US Patent 5,644,642, 7/1/97. Filed 4/3/95.

“Optical Coherence Tomography Assisted Ophthalmologic Surgical Microscope” Issued US Patent 5,493,109, 2/20/96. Filed 8/18/94.

“Method and Apparatus for Optical Coherence Tomographic Fundus Imaging without Vignetting” Issued US Patent 5,537,162, 6/16/96. Filed 12/17/93.

“Method and Apparatus for High Speed Longitudinal Scanning in Imaging Systems” Issued US Patent 6,191,862 2/20/01.

“Fiber Optic Needle Probes for Optical Coherence Tomography Imaging” Patent Pending.

“Micro-Lens for Miniature Optical Probes” Patent Pending.

“Method and Apparatus for Performing Optical Frequency Domain Reflectometry” Issued US Patent 6,160,826. 12/12/00. Filed 1999.

“Broadband Light Source System and Method Thereof” Patent Pending.

“Apparatus and Method for Selective Data Collection and Signal to Noise Ratio Enhancement Using Optical Coherence Tomography” Patent Pending Filed 4/6/01.

“Fiber Optic Endoscopic Gastrointestinal Probe” Patent Pending.

License Grant

The first agreement gives licensee exclusive rights  from the government organization to manufacture and distribute a Nonradioactive isotope version of NASA’s low intensity X-ray and gamma ray imaging device (patent no. 4,142,101).  

This technology provides the ability to amplify X-rays that have been converted to visible light.  The FluoroScan System is a low intensity, real time X-ray imaging device which provides high resolution images at radiation levels and at a cost well below those of conventional X-ray and fluoroscopic equipment.  The FluoroScan System technology is based on a micro channel plate image intensifier commonly known as a night vision intensifier.