Royalty Report: Medical, Device, Diagnostic – Collection: 289542

License Grant

If, and only if, Licensor exercises its option for a license under the CIC Patents pursuant to this agreement, Licensor shall grant (and will cause its Affiliates to grant) to Licensee and its Affiliates the right and option until the expiration of thirty (30) months from the Effective Date or ninety (90) days from the date Licensor exercises its option, whichever is later in time, to obtain a non-exclusive, worldwide, non-transferable, royalty-bearing license under the Savacor Patents.

License Property

Savacor Patents shall mean those patents and patent applications, and all patents and patent applications claiming priority therefrom, that Licensor or its Affiliates acquired from Savacor, Ind. as set forth.  The Savacor Patents shall include the sublicensable patents and patent applications of Cedars Sinai Medical Center listed.

6,970,742 – Method for detecting, diagnosing, and treating cardiovascular disease
6,328,699 – Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure

Field of Use

“CRM Products” means devices for monitoring or electrically stimulating or shocking the heart which are suitable for chronic implantation, in whole or in part, by or with human patients. The term “CRM Products” includes, without limitation cardiac pacemakers, antitachycardia pacemakers, cardiac resynchronization therapy systems, cardioverters, and defibrillators, including combinations thereof; loop recording systems, implantable cardiac monitoring systems, implantable hemodynamic monitoring systems, pulse generators and other waveform generators for such devices; cardiac lead implant catheters and associated tools; leads, electrodes, sensors, capacitors, batteries, power sources, and all other components for such devices; mechanisms for coupling such generators in a stimulating, shocking, sensing, or monitoring relationship to the heart; and data dispensing, processing, and gathering systems for such devices, including programmers, pacing system analyzers, defibrillation system analyzers, testers, encoders, decoders, transtelephonic and other remote monitoring systems and services for use with implantable devices, transmitters, receivers, and computer software-controlled systems, and including the software. The term “CRM Products” excludes, by way of example and not limitation, nerve stimulators (unless used for cardiac therapy), bone growth stimulators, drug release pumps, cardiac pumps, artificial hearts, prosthetic heart valves, catheter ablation devices, imaging systems, catheter location systems, apparatus for revascularization or correction of other physical defects in heart tissue, arrhythmia mapping devices (except as part of an implantable cardiac therapy or monitoring device), angioplasty devices and EKG monitors (other than cardiac stimulation device programmers or other telemetry devices for use with implantable pulse generators or cardiac monitors) which are standalone, non-ambulatory and not intended for transtelephonic or other remote monitoring.

License Grant

The parties are adverse parties following currently pending litigation matters, which are being terminated pursuant to a Settlement Agreement.

The parties are engaged in, inter alia, the design, development, manufacture, and sale of CRM Products.

Pursuant to the Settlement Agreement, the parties have agreed to terminate certain cases and have agreed to enter into a cross licensing of certain rights under the Licensed Patents and Sublicensable Patents.

Licensor grants a non-exclusive, irrevocable, perpetual, worldwide license or sublicense, as the case may be, without the right to sublicense, under all Licensed Patents of Licensor to make, have made, use, sell, have sold, offer to sell, distribute, have distributed, and otherwise dispose of CRM Products, including supplying or causing to be supplied components thereof for use therein, and further including importing CRM Products, including components thereof for use therein, into any jurisdiction where Licensed Patents of Licensor are effective.

Licensor shall grant the right and option until the expiration of thirty (30) months from the Effective Date or ninety (90) days from the date Licensor exercises its option, whichever is later in time, to obtain a non-exclusive, worldwide, non-transferable, license under the specific Patents.

License Property

CRM Products means devices for monitoring or electrically stimulating or shocking the heart which are suitable for chronic implantation, in whole or in part, by or with human patients. The term CRM Products includes, without limitation cardiac pacemakers, antitachycardia pacemakers, cardiac resynchronization therapy systems, cardioverters, and defibrillators, including combinations thereof; loop recording systems, implantable cardiac monitoring systems, implantable hemodynamic monitoring systems, pulse generators and other waveform generators for such devices; cardiac lead implant catheters and associated tools; leads, electrodes, sensors, capacitors, batteries, power sources, and all other components for such devices; mechanisms for coupling such generators in a stimulating, shocking, sensing, or monitoring relationship to the heart; and data dispensing, processing, and gathering systems for such devices, including programmers, pacing system analyzers, defibrillation system analyzers, testers, encoders, decoders, transtelephonic and other remote monitoring systems and services for use with implantable devices, transmitters, receivers, and computer software-controlled systems, and including the software.

Field of Use

The field of use is the medical (pacemaker) industry.

License Grant

The parties are adverse parties following currently pending litigation matters, which are being terminated pursuant to a Settlement Agreement.

The parties are engaged in, inter alia, the design, development, manufacture, and sale of CRM Products.

Pursuant to the Settlement Agreement, the parties have agreed to terminate certain cases and have agreed to enter into a cross licensing of certain rights under the Licensed Patents and Sublicensable Patents.

Licensor grants a non-exclusive, irrevocable, perpetual, worldwide license or sublicense, as the case may be, without the right to sublicense, under all Licensed Patents of Licensor to make, have made, use, sell, have sold, offer to sell, distribute, have distributed, and otherwise dispose of CRM Products, including supplying or causing to be supplied components thereof for use therein, and further including importing CRM Products, including components thereof for use therein, into any jurisdiction where Licensed Patents of Licensor are effective.

Licensor grants the right and option for a period of thirty (30) months from the Effective Date to obtain a non-exclusive, worldwide, non-transferable, royalty-bearing license under the CIC Patents.

License Property

CRM Products means devices for monitoring or electrically stimulating or shocking the heart which are suitable for chronic implantation, in whole or in part, by or with human patients. The term CRM Products includes, without limitation cardiac pacemakers, antitachycardia pacemakers, cardiac resynchronization therapy systems, cardioverters, and defibrillators, including combinations thereof; loop recording systems, implantable cardiac monitoring systems, implantable hemodynamic monitoring systems, pulse generators and other waveform generators for such devices; cardiac lead implant catheters and associated tools; leads, electrodes, sensors, capacitors, batteries, power sources, and all other components for such devices; mechanisms for coupling such generators in a stimulating, shocking, sensing, or monitoring relationship to the heart; and data dispensing, processing, and gathering systems for such devices, including programmers, pacing system analyzers, defibrillation system analyzers, testers, encoders, decoders, transtelephonic and other remote monitoring systems and services for use with implantable devices, transmitters, receivers, and computer software-controlled systems, and including the software.

Field of Use

The field of use is the pacemaker monitoring industry.

License Grant

The Licensor hereby grants to the Licensee, and the Swiss Licensee hereby accepts, a non-exclusive, royalty-bearing right and license under the Licensed IP to use, make, have made, sell, offer to sell, distribute and import Licensed Products in the Territory during the Term for applications within the Field of Use; provided, however, that upon the occurrence of a License Conversion Event, the portion of the non-exclusive license consisting of the non-exclusive, royalty-bearing license to sell, offer to sell, distribute and import Licensed Products in the Territory during the Term for applications within the Field of Use (the Non-Exclusive Distribution License) shall immediately, and without the need for any action on the part of either party, convert into an exclusive, royalty-bearing license to sell, offer to sell, distribute and import Licensed Products in the Territory during the Term for applications within the Field of Use (Exclusive Distribution License); provided, however, that the exclusivity of such Exclusive Distribution License shall be subject to, and shall not impact, any license rights previously granted in favor of Greatbatch pursuant to the Greatbatch License Agreement; provided, further, however, that if the Licensee fails to obtain FDA Approval for the Licensed Products within six (6) years after the License Conversion Date, the Exclusive Distribution License shall become convertible by the Licensor, at its sole discretion, back into a Non-Exclusive Distribution License. For the avoidance of doubt, during the Term, the non-exclusive, royalty-bearing license to use, make and have made Licensed Products in the Territory during the Term for applications within the Field of Use shall continuously remain a non-exclusive license.  License Conversion Event means the first to occur of (i) receipt of a Conformité Européenne (CE) mark for the Licensed Products that permits sale of such Licensed Products within the European Economic Area for application within the Field of Use; (ii) receipt of FDA Approval or (iii) completion by the Licensee of a human clinical study demonstrating safety and efficacy required to obtain (A) a Conformité Européenne (CE) mark for the Licensed Products that permits sale of such Licensed Products within the European Economic Area for applications within the Field of Use, or (B) FDA Approval.

License Property

United States (U.S.) Licensed Patents
8,954,148  Key Fob controller for an implantable neurostimulator  
8,483,836  Automated search to identify a location for electrical stimulation to treat a patient
8,515,545  Current steering neurostimulator device with unidirectional current sources
8,571,667  Active current control using the enclosure of an implanted pulse generator
8,738,153  Implantable lead with braided conductors
8,757,485  System and method for using clinician programmer and clinician programming data for inventory and manufacturing prediction and control
8,761,892  Active current control using the enclosure of an implanted pulse generator
8,761,897  Method and system of graphical representation of lead connector block and implantable pulse generators on a clinician programmer
8,781,592  Identifying an area for electrical stimulation to treat a patient
8,812,125  Systems and methods for the identification and association of medical devices
8,868,199  System and method of compressing medical maps for pulse generator or database storage
8,874,219  Arbitrary waveform generator and neural stimulation application
8,903,496  Clinician programming system and method
8,983,616  Method and system for associating patient records with pulse generators
8,996,115  Charge balancing for arbitrary waveform generator and neural stimulation application
8,996,117  Arbitrary waveform generator and neural stimulation application with scalable waveform feature
8,700,175  Devices and methods for visually indicating the alignment of a transcutaneous energy transfer device over an implanted medical device
9,002,466  Diversity antennas for neurostimulator programming devices
9,031,664  Current steering neurostimulator device with unidirectional current sources
9,031,666  Devices and methods for visually indicating the alignment of a transcutaneous energy transfer device over an implanted medical device
9,067,074  Automated search to identify a location for electrical stimulation to treat a patient
9,072,903  System and method of establishing a protocol for providing electrical stimulation with a stimulation system to treat a patient
9,098,610  Communication for implantable medical devices
9,101,767  Measuring load impedance with active stimulation pulses in an mplanted pulse generator
9,126,043  Patient handheld device for use with a spinal cord stimulation system
D663,035  Two-port implantable medical device
D665,086  Three-port implantable medical device
D665,087  Multi-port implantable medical device
D671,900  Pocket controller for implantable neurostimulator
D698,779  Clinician programmer for implantable neurostimulator

Field of Use

Field of Use means deep brain stimulation for movement disorders (i.e. Parkinson’s disease and/or essential tremor).

License Grant

The parties desire to amend and restate the relationship between the parties that currently exists by virtue of the Exclusive License Agreement dated  January 30, 1973,  to restate the grant to assigned Licensee of the sole and exclusive worldwide license for the use of said patents, patent applications, and inventions.

Licensor grants the sole and exclusive license and right to manufacture, use, sell, rent and lease or otherwise dispose of any and all devices under the Patent Rights and or any Improvements thereof throughout the United States, its territories and possessions, and in any and all foreign countries, subject to the terms and conditions set forth in this Exclusive License Agreement.

License Property

The licensed property includes Implantable Defibrillators, lead devices and other device for use with an Implantable Defibrillator.

Defibrillation is a treatment for life-threatening cardiac dysrhythmias, specifically ventricular fibrillation (VF) and non-perfusing ventricular tachycardia (VT). A defibrillator delivers a dose of electric current (often called a countershock) to the heart.

Field of Use

The field of use is Implantable Defibrillators.  This agreement pertains to the medical industry.

License Grant

Licensor grants a worldwide, non-transferable, and non-sub licensable license to make, have made, use and sell Licensed Products in the Field of Use.  The licensed granted shall be co-exclusive, meaning that Licensor or any Affiliate of Licensor shall also have the worldwide right to make, have made, use, sell or otherwise commercialize and exploit the Licensed Technology in the Field of Use, provided that Licensor shall not grant any licenses to the Licensed Technology in the Field of Use during the term of this Agreement.

License Property

Licensor has developed certain technology related to catheter navigation and mapping.

Licensor is a medical device company, with products including cardiac devices, cranial and spine robotics, insulin pumps, surgical tools, and patient monitoring systems.

This agreement is for the technology, patent and applications are for Catheter Mapping System and Application, including, specifically, U.S Patent No 5,697,377, and all trade secrets and know-how owned by Licensor prior to the date of this Agreement which relate specifically and directly to 3-D electrode localization devices and techniques as disclosed in the patents or patent applications, including but not necessarily limited to software developed specifically to practice the inventions disclosed in the patents included in the Licensed Technology, and new patents arising out of patent applications filed, or inventions reduced to practice and relate specifically and directly to 3-D electrode localization devices and techniques.

Field of Use

The Field of Use shall mean electrophysiological intracardiac mapping applications for the treatment of cardiac arrhythmias.

Licensee is engaged in the development of the EnSite diagnostic catheter and clinical workstation for use by electrophysiologists in diagnosing and mapping abnormal heart rhythms known as tachycardias.

License Grant

The University hereby  grants to the Company an exclusive license to make, have made, use, and sell the Licensed Product(s) and to provide Licensed Service(s) in the United  States and worldwide under the Patent Rights in the Exclusive License Field.

License Property

Patent Rights shall mean the U.S. patent No. 5,217,010, issued June 8, 1993, and assigned to JHU entitled ECG Amplifier and Cardiac Pacemaker for Use During Magnetic Resonance Imaging (hereinafter the Patent).  Licensed Service(s)' means the performance on behalf of a third party of any method including the design, testing, implantation or the manufacture of any produce or the use of any product or composition which would constitute, but for the license granted to the Company pursuant to this Agreement, an infringement of a claim of the Patent Rights, (infringement shall include, but not be limited to, direct, contributory or inducement to infringe).

Field of Use

Co-exclusive License field shall mean temporary pacemakers.

Excluded License field shall mean MRI-guided temporary catheters that do not provide a pacemaker function.

License Grant

The Company grants an exclusive license to use the HeartSine Technology to develop, manufacture and commercialize Automatic Defibrillator Modules which shall operate as a subcomponent of a Patient Monitoring System for use in hospitals and in freestanding medical or surgical clinics which provide cardiovascular services to patients and obtain an option to an exclusive license to use the HeartSine Technology to develop, manufacture and commercialize stand alone defibrillation devices which shall operate as a prophylactic diagnostic and therapeutic monitor for patients in hospitals and in free-standing medical or surgical clinics which provide cardiovascular services to patients, including, but not limited to, the Powerheart; certain intellectual property related to external defibrillation that utilizes biphasic waveform technology and solid state switching technology.

License Property

Patient Monitoring System shall mean a device which is capable of monitoring of physiologic functions of a patient and displaying those physiologic functions locally (on an attached monitor) or through transmission to a monitor external to the system.

Field of Use

Field shall mean the application of the HeartSine Technology for the development and manufacture of Licensed Products for use in hospitals and in freestanding medical or surgical clinics as a subcomponent of a Patient Monitoring System.

License Grant

The Licensee agreed to license from Licensor, a non-profit health care organization, specific patents relating to Products that treat irregular heartbeats (arrhythmias).

License Property

ICDs are electronic devices that are implanted within the body and are connected to the heart with defibrillator leads.  These devices monitor the patient's heartbeat and, in the event of VT or VF, deliver an electrical shock to return the heartbeat to normal rhythm.

License Grant

This agreement is an exclusive, worldwide license to the porcine tissue.  Along with this license agreement, the Parties entered into a supply agreement, whereby Licensor would be the exclusive supplier to Licensee of the licensed porcine tissue.

License Property

This agreement is an exclusive, worldwide license to the porcine tissue for use in the Licensee’s Cardiac Patch and CanGaroo products, subject to certain co-exclusive rights retained by Licensor.

The SIS ECM biomaterial used in the medical device products are manufactured by Licensor.  CanGaroo is soft and pliable and is designed to conform to the implantable device for easy handling and implantation.  The SIS ECM is designed to mitigate the biologic foreign body response that normally occurs around the electronic device.

The CanGaroo envelope is constructed from perforated, multi-laminate sheets of decellularized, non-crosslinked, lyophilized small intestine submucosa (SIS) extracellular matrix (ECM), derived from porcine small intestinal submucosa, a natural biomaterial, which is rich in natural growth factors, structural proteins and collagens.

Field of Use

Specifically, the field of use is with neuromodulation devices in addition to cardiovascular devices; for use in the Licensee’s Cardiac Patch and CanGaroo products.

CanGaroo was designed to mitigate complications deriving from implantable electronic devices and the shortcomings of synthetic envelopes. We believe that CanGaroo is the only biological product that forms a natural, systemically vascularized pocket that conforms to and securely holds implantable electronic devices. CanGaroo is cleared for use with pacemaker pulse generators, defibrillators and other cardiac implantable electronic devices as well as vagus nerve stimulators, spinal cord neuromodulators, deep brain stimulators and sacral nerve stimulators.

License Grant

This license is granted upon execution of the option to license and already accepted by Licensee. With Licensee exercising the option to license, Licensee is additionally granted  a non-exclusive, sublicensable license in the field for the countries Licensor is not able to fulfill Sections 3.8 or 3.9 to use any Background Patents necessary for the use and exploitation of the Catheter Technology, Peripheral Technology or Product to the extent related to the Application.

License Property

Licensor is a leading company developing, manufacturing and selling devices as well as developing treatment plans for various medical indications, such as deep brain stimulation or cardiac ablation.

Product shall mean and comprise a combination of hardware, software and workflow procedures allowing the performance of the Application or parts thereof under simultaneous MR imaging, which the Parties wish to develop under this Agreement and which is defined in more detail in Agreement. The Product shall be integrated and developed by Licensor as a medical product according to applicable local medical product regulations including, but not limited to the EU and the USA, integrating and combining the Software, MR System, Catheter Technology and Peripheral Technology. The summary describes the components and operation of an MRI-guided EP ablation system. The system uses active (signal receiving) invasive devices and special software for customized image reconstruction and display. In the prototyping phase, the software component of the system will run on a computer attached to the scanner, while for the product version, the software component of the system will run on the scanners host computer.

MR System shall mean any applicable Licensee MR system. Target MR System for the Product include the Magnetom Verio and the Magnetom Espree. Other MR System might be added after mutual agreement. The MR System is currently provided by Licensee as a medical product according to applicable local medical product regulations in several countries, including, but not limited to, the EU, Canada and the USA.

Software means software and dedicated MR sequences, which are developed by Licensee according to requirement specifications by Licensor. These specifications are defined in the Agreement. For the avoidance of doubt, Software does not include the base modules IFE and IRTTT, or any further developments or future versions of IFE or IRTTT, but only the dedicated plug in module dedicated to the workflow of the Product developed under this Agreement.

Background Patents shall mean patent applications, patents, utility models and other statutory protection with regard to MR System, Application, Catheter Technology, Peripheral Technology, Software, Integration or the Product under which one PARTY is the owner and/or has the right of determination at any time during the term of this Agreement and which are not a Development Result.

Catheter Technology shall mean and comprise the invasive medical devices (e.g. guidewire, catheters) supplied by Licensor for the use in the Product and within and in close proximity to an MR System and which are defined in this Agreement. The Catheter Technology shall be provided by Licensor as a medical product according to applicable local medical product regulations including, but not limited to, the EU and the USA.

Peripheral Technology means hardware and software required by the user to perform the Application with the Product and which is not already included in Catheter Technology or Software or MR System.

Application shall mean the treatment of cardiac arrhythmia by catheter mediated ablation under simultaneous MR imaging and catheter mediated cardiac electrophysiological mapping under simultaneous MR imaging by using the Product. In the event the width of an Application is specified through guidelines of regulatory bodies like SFDA, CE, FDA, such specification shall apply.

Field of Use

Licensee is a leading company in developing, manufacturing and selling Magnetic Resonance (“MR”) Imaging systems, which are used worldwide for diagnostics of a wide variety of medical indications. MR imaging is free of ionizing radiation and is therefore well-suited for continued supervision of treatment procedures.

The Parties wish to establish a Cooperation and Development Agreement aiming at a combination of the capabilities of Catheter Ablation and MR imaging in developing a product combination that allows performing the treatment of cardiac arrhythmias by catheter mediated ablation and catheter mediated cardiac electrophysiological mapping procedure under simultaneous MR imaging for worldwide marketing and sales.  The Parties agree that this treatment consists of a procedure with the involvement of different medical devices, including catheters and mapping technology as well as MR imaging guidance. The Parties intend to develop an MR workflow with all required components integrated into the special requirements of the MR environment.

Field shall mean treatment of cardiac arrhythmia by catheter mediated ablation under simultaneous MR imaging and catheter mediated cardiac electrophysiological mapping under simultaneous MR imaging.

License Grant

Licensor grants to Licensee a worldwide, exclusive license to make, have made, use and sell Royalty Products.

License Property

Royalty Product means any Lead Extractor covered by a claim of an unexpired patent in the Licensed Intellectual Property or employing Licensor Confidential Information in the Licensed Intellectual Property; provided that the laser generators and other capital equipment of Licensee will not be considered Royalty Product. Lead Extractors sold for the purpose of clinical trials required for obtaining government approval to market in any country shall not be deemed Royalty Product.

Lead Extractor means a device for aiding in removal of medical devices such as pacing and defibrillation leads or catheters.

Licensed Intellectual Property means (1) All U.S. patents and patent applications owned by or licensed to, with the right to sublicense, Licensor which are now or during the term of this Agreement developed for use in the laser extraction of leads or catheters, including U.S. Patent 5,423,806 entitled 'Laser Extractor for an Implanted Object' and U.S. Patent Application 08/153,715 entitled 'Heart Synchronized Extractor for an Implanted Object'; (2) all patent rights derived from such patents and patent applications, including but not limited to foreign rights, divisionals, continuations, continuations in part, re-issues, and reexaminations; and (3) any confidential information provided to Licensee by Licensor (a) under the terms of the Agreement for Mutual Exchange of Confidential Information between Licensee and Licensor dated May 21, 1991 (the Confidentiality Agreement), (b) in written form and marked as proprietary, confidential or the like, before and during the development of Licensee products, including but not limited to the original concept drawings and information disclosures (collectively the Licensor Confidential Information).  Licensor Confidential Information shall not, however, include information which
    (i)   is or was known to Licensee prior to receipt thereof under this Agreement or the Confidentiality Agreement, as evidenced by written records;
    (ii)  is disclosed without restriction to Licensee in good faith by a third party who is in lawful possession thereof and who has the right to make such disclosure;
    (iii) is or shall have become public knowledge, by publication or otherwise, through no fault of Licensee;  
    (iv)  is discovered by Licensee completely without reference to Licensor Confidential Information; or
    (v)   is transmitted to Licensee by Licensor after Licensor received notification in writing from Licensee that Licensee did not desire to receive any further Licensor Confidential information.

U.S. Patent 5,423,806 entitled Laser Extractor for an Implanted Object
U.S. Patent Application 08/153,715 entitled Heart Synchronized Extractor for an Implanted Object

Licensor has developed technology relating to laser lead extraction and owns intellectual property related thereto.

Field of Use

The field of use is in the medical industry relating to devices for aiding in removal of medical devices such as pacing and defibrillation leads or catheters.

Licensee develops, manufactures, markets, and distributes its technology for interventional cardiovascular therapy. The Companys system is used in applications such as coronary angioplasty and the removal of pacemaker leads.

License Grant

Assignor sells, assigns, conveys, transfers and delivers to Assignee, its successors and permitted assigns, the Spot Catheter Patents and the Spot Catheter Technology and the Linear Catheter Patents and the Linear Catheter Technology to be used only in the Field of Use.

License Property

Assignor is in the business of developing implantable cardiac defibrillators and electrophysiology catheters. The IP includes patents and U.S. Patent Applications, Serial Nos. 08/496,947 and 09/073,651 and corresponding foreign patents.

Field of Use

The Field of Use shall mean the radio frequency (RF) cardiac ablation therapy field.  This agreement pertains to the medical industry.

License Grant

The Company hereby grants the worldwide right to manufacture, cause to be manufactured, promote, sell, market, distribute and use the Pump Technology; programmable implantable insulin pump system.

License Property

Implantable microinfusion pump systems intended for in vivo use; utilizes Pump Technology for diabetes or non-diabetes applications. Glucose Controllers, Glucose Monitors, Long-Term Glucose Sensors and the abdominal lead that connects the implantable pump to a Long-Term Glucose Sensor are not Licensed Products.  An apparatus or system which utilizes Glucose Sensing Technology to control an insulin infusion device in a human or in an animal.   Any monitor product utilizing Glucose Sensing Technology to provide indications of glucose concentration or changes in glucose concentration in a human or in an animal.

License Grant

The Licensor, a nonprofit American academic medical center,  grants to Company the following (a) an exclusive license with the right to sublicense, within the Field and Territory, under the Patent Rights to make, have made, use, offer for sale, sell, and import Licensed Products; and (b) a nonexclusive license, with the right to sublicense, within the Field and Territory, to use the Know-How to develop, make, have made, use, offer for sale, sell, and import Licensed Products.

License Property

Patent Rights shall mean U.S. patent number 8,538,501, and any re-examinations and re-issues thereof, as well as extensions and supplementary protection certificates and any foreign counterpart of any of the foregoing.

8,538,501 – Mapping and ablation catheter system

Licensed Product shall mean any product, process, or service which (a) the manufacture, use, sale, offer for sale or importation of which infringes an issued claim of the Patent Rights, or that would infringe but for the exception in 35 U.S.C. §271(e)(1), or similar exception in the United States or other countries; or (b) the development, manufacture, use, sale, offer for sale or importation of which incorporates, uses, was derived from, identified by, validated, or developed in whole or in part using the Know-How.

Field of Use

Field shall mean a mapping and ablation catheter system.
Pure EP is a computerized system designed to acquire, digitize, measure, display and store electrocardiographic and intracardiac signals for patients undergoing electrophysiology procedures.
The product sets out to assist electrophysiologists with decision-making during EP procedures in patients with abnormal heart rates and rhythms.

License Grant

Licensor grants to Licensee a worldwide non exclusive non transferable license under Licensed Technology to make, use, have made or sell Licensed Products.

License Property

Licensed Product(s) means external defibrillator(s) for defibrillating the atria of a heart with temporary catheters and/or heart wires for internal defibrillation which is covered in the country of manufacture and/or sale by one or more claims of a patent included in the Licensed Technology.  Licensor owns the exclusive rights to a U.S. Patent No. 5,207,219 and foreign counterparts thereof (hereinafter referred to as (Licensed Technology).

Field of Use

The rights granted apply to the heart.

License Grant

Licensor hereby grants Licensee its Affiliates an exclusive, worldwide, sublicensable license in and to Licensor’s IP to (i) use, make, have made, sell, offer to sell, import, modify, distribute, perform and otherwise exploit the Exclusive Products and (ii) enforce such Licensor’s IP against other Persons and collect past, present and future damages from any other Person’s infringement or misappropriation of Licensor’s IP but all of the foregoing rights and licenses are limited to the Field.

License Property

“Non-Drug Coated” means devices not coated with a drug or a drug eluting polymer coating.  Exclusive Product/Services  Vascular stents including coronary, neuro or peripheral applications of coated or uncoated stents; Embolic protection devices, aneurysm coils and all other vascular implants (other than stents); RF ablation probes and ablation fluid.

Non-Exclusive Product/Services Biopsy needles, including aspiration, cutting needles and breast localization needles; Interventional guidewires (for use in all applications); Interventional vascular catheters (<6 hours), including PTCA, predilation, etc.; Indwelling vascular catheters (>6 hours), including CVC, PICC, etc.; Pacemakers, including leads; Implantable cardiac defibrillators and related devices, including their leads; Auditory implants, e.g. cochlear implants; Neuro stimulation including deep brain.

Field of Use

“Field” means systems, devices, components, compositions and processes for magnetic resonance imaging, including without limitation for providing or enhancing (a) safety, effectiveness, image quality and/or image compatibility or (b) the visualization of medical devices in vivo.

License Grant

The Company hereby grants within the Field of Use the exclusive rights to several ultrasound technologies for use in the field of electrophysiology.

License Property

Echomark (5,076,278)  means EchoCath's proprietary catheter positioning system which is covered by the Patents.

EchoEye (5,373,845) means proprietary technology for allowing clinicians to view tissues and organs in three-dimensional real-time and provide forward looking intravascular images and guidance for ultrasound guided procedures, and covered by the Patents.

ColorMark (5,329,927) means proprietary needle and stylete positioning system which is covered by the Patents.

Field of Use

Field of Use shall include the application of the EchoMark, EchoEye and ColorMark technologies as they apply to any and all systems and products which are designed and/or manufactured for electrophysiology applications to include but not limited to mapping, ablation and internal cardioversion.  The Field of Use specifically excludes permanent pacemaker leads and permanent defibrillator leads attached to permanent implantable pulse generators.

License Grant

Foundation hereby grants to Licensee royalty-bearing, license, with the right to sublicense to make, have made, lease, offer to lease, use, sell, offer for sale, market, promote, advertise, import, research, develop and commercialize Licensed Products in the Field only, in the Territory; provided that with respect to Externals, the foregoing license shall only apply to the extent that such Externals are used in connection with the foregoing licensed activities involving Licensed Products other than Externals.

License Property

“Licensed Product” means (i) Epione and (ii) all Externals sold or distributed solely for use with Epione.

Licensed Products are worldwide for the treatment of (i) chronic pain in humans through the application of electrical energy to the nervous system, (ii) inflammatory conditions of the human body through the application of electrical energy to the vagus nerve, a nerve that interfaces with parasympathetic control of the heart, lungs and digestive tract and (iii) urinary and fecal dysfunction in humans through the application of electrical energy anywhere in or on the human body, excluding, in each case, any product or method that involves the placement of electrodes or the administration of electrical stimulation inside the cranial cavity or to the ocular nervous system or the auditory nervous system.

“Epione” means the Epione implantable pulse generator, leads, external pulse generator, charging system and related system components and software

“Externals” means any peripheral or auxiliary device that can be used in connection with, or operate in concert with, Epione, including the components that when assembled comprise such device, and including surgical procedure tools, protection apparatus, controllers, battery chargers, patient remote controller, programmer, software and electrodes.

Field of Use

“Initial Field” means (i) the treatment of chronic pain in humans through the application of electrical energy to the nervous system; and (ii) the treatment of inflammatory conditions of the human body through the application of electrical energy to the vagus nerve.

License Grant

University Licensor hereby sells, assigns and transfers to Licensee, its entire right, title and interest, in the Intellectual Property,developed by Drs. Xiang Wang and Hun H. Sun, relating to a cardiac monitoring system.Patents5443073 issued 8/22/95; 5423326 issued 6/13/95; 5309917 issued 5/10/94.

Field of Use

The rights granted apply to a cardiac monitoring system.