Royalty Report: Cancer, Medical, Device – Collection: 286475

$150.00

Curated Royalty Rate Report
Category: Technology Licenses, Created On: 2022-04-28, Record Count: 9

Description

This collection of transactions and supporting information was developed using our AI algorithm to curate similar royalty reports into a cohesive collection to support your licensing, transfer pricing or other transaction scenarios where documented royalty rates and/or deal terms are important.
Category: Technology Licenses
Created On: 2022-04-28
Record Count: 9

Primary Industries

  • Cancer
  • Medical
  • Device
  • Radiation
  • Therapeutic
  • Delivery
  • Supply
  • Drugs
  • Disease

IPSCIO Report Record List

Below you will find the records curated into this collection.  This summary includes the complete licensed property description so that you can review and determine if this collection covers the topics, technology or transaction type that is relevant for your needs.  The full report will include all relevant deal data such as the royalty base, agreement date, term description, royalty rates and other deal terms.  For reference, here is a sample of a full IPSCIO curated royalty rate report: Sample Report

IPSCIO Record ID: 286475

License Grant
The Institute, a private nonprofit applied science and technology development company, has granted the Company an exclusive license to patents covering the manufacturing, processing and applications of RadioGelâ„¢.

As a result of this Amendment, the Company has agreed to revised terms regarding the license fee and royalty rate.

License Property
RadioGel™ is comprised of a hydrogel, or a substance that is liquid at room temperature and then gels when reaching body temperature after injection into a tumor. In the gel are small, one micron, yttrium-90 phosphate particles (“Y-90”). Once injected, these inert particles are locked in place inside the tumor by the gel, delivering a very high local radiation dose. The radiation is beta, consisting of high-speed electrons. These electrons only travel a short distance so the device can deliver high radiation to the tumor with minimal dose to the surrounding tissue. Optimally, patients can go home immediately following treatment without the risk of radiation exposure to family members. Since Y-90 has a half-life of 2.7 days, the radioactively drops to 5% of its original value after ten days.
Field of Use
RadioGelâ„¢ is a brachytherapy device comprising highly insoluble Yttrium-90 particles delivered by needle injection using a water-polymer composite for high-dose treatment of non-resectable solid tumors that cannot be treated effectively by any other means. It is designed for maximum safety to deliver a high, pure-beta radiation dose to target (tumor) tissue, with comparatively small-to-negligible radiation doses to adjacent normal tissues, and with negligible radiation dose to any major organ or tissue in the body.

IPSCIO Record ID: 264174

License Grant
The Company has agreed to revised terms regarding the license fee and to increase the royalty fee on net sales as regards to the use of its patented RadioGelâ„¢ technology from a private nonprofit applied science and technology development company.
License Property
RadioGelâ„¢ is an injectable particle-gel, for brachytherapy radiation treatment of cancerous tumors in people and animals.

RadioGelâ„¢ is a brachytherapy device comprising highly insoluble Yttrium-90 particles delivered by needle injection using a water-polymer composite for high-dose treatment of non-resectable solid tumors that cannot be treated effectively by any other means. It is designed for maximum safety to deliver a high, pure-beta radiation dose to target (tumor) tissue, with comparatively small-to-negligible radiation doses to adjacent normal tissues, and with negligible radiation dose to any major organ or tissue in the body.

RadioGel™ is comprised of a hydrogel, or a substance that is liquid at room temperature and then gels when reaching body temperature after injection into a tumor. In the gel are small, one micron, yttrium-90 phosphate particles (“Y-90”). Once injected, these inert particles are locked in place inside the tumor by the gel, delivering a very high local radiation dose. The radiation is beta, consisting of high-speed electrons. These electrons only travel a short distance so the device can deliver high radiation to the tumor with minimal dose to the surrounding tissue. Optimally, patients can go home immediately following treatment without the risk of radiation exposure to family members. Since Y-90 has a half-life of 2.7 days, the radioactively drops to 5% of its original value after ten days.

Field of Use
This agreement pertains to the medical industry relating to a radiation oncology medical device for the development of the yttrium-90 based brachytherapy device RadioGelâ„¢ for the treatment of non-resectable tumors.

IPSCIO Record ID: 221773

License Grant
Licensor, a private nonprofit applied science and technology development company, hereby grants to Licensee to the extent of the Licensed Field and Licensed Territory, an exclusive license to make, have made, use and sell Licensed Products.

The license granted shall be subject to any rights the Government of the United States of America may presently have or may assert in the future for any reason including, but not limited to, those rights set forth.

Licensor reserves the right to (i) practice the Patents for research, development and demonstration purposes for itself and others, (ii) nonexclusively license the Patents to nonprofit institutions that collaborate with Licensee for research, development, and demonstration purposes only, and (iii) license the Patents in fields not exclusively licensed herein.

License Property
Licensed Products means any and all products incorporating or services utilizing one or more claims of the licensed Patents.

Patent or Patents means the following patents, and all reissues, reexaminations, substitutes, and extensions thereof
Issued Patents

Title Stimulus Sensitive Gel with Radioisotope and Methods of Making (Licensee IPID 11505-E
Master Patent ID 1201)*  
Country

Patent Number
  
Date Granted
U.S.

6,296,831

October 2, 2001

Title Stimulus Sensitive Gel with Radioisotope and Methods of Making (Licensee IPID 11505-E
CON Master Patent ID 1204)*
Country

Patent Number

Date Granted
U.S.

6,869,588

March 22, 2005

Title Stimulus Sensitive Gel with Radioisotope and Methods of Making (Licensee IPID 11505-E
Master Patent ID 1197)*
Country

Patent Number

Date Granted
Canada

2,327,325

January 24, 2006

Title Thermogelling Biodegradable Aqueous Polymer Solution (Licensee IPID 12483-B Master Patent ID 1892)†

Country

Patent Number

Date Granted
U.S.

6,841,617

January 11, 2005

Title Thermogelling Oligopeptide Polymers (Licensee IPID 12483- B CIP Master Patent ID 1893) †
Country

Patent Number

Date Granted

U.S.

7,087,244

August 8, 2006

Title Thermogelling Biodegradable Aqueous Polymer Solution (Licensee IPID 12483-B Master Patent ID 1889) †

Country

Patent Number

Date Granted
Canada

2,423,488

July 13, 2010

Title Multiple Stimulus Reversible Hydrogels (Licensee IPID 12575-E Master Patent ID 1963)*
Country

Patent Number

Date Granted

U.S.

6,660,247

December 9, 2003

Title Multiple Stimulus Reversible Hydrogels (Licensee IPID 12575-E CON Master Patent ID 4425)*

Country

Patent Number
  
Date Granted
U.S.

7,033,571

April 25, 2006

RadioGelâ„¢ device is a brachytherapy device comprising highly insoluble Yttrium-90 particles delivered by needle injection using a water-polymer composite for high-dose treatment of non-resectable solid tumors that cannot be treated effectively by any other means. It is designed for maximum safety to deliver a high, pure-beta radiation dose to target (tumor) tissue, with comparatively small-to-negligible radiation doses to adjacent normal tissues, and with negligible radiation dose to any major organ or tissue in the body.

Brachytherapy uses radiation to destroy cancerous tumors by placing a radioactive isotope inside or next to the treatment area.

Field of Use
Licensed Field means, and is limited to, medical and veterinary therapeutic radioisotope delivery.

IPSCIO Record ID: 266765

License Grant
For the License to the Kaminski Patent Family and Wahl Patent Family, the Licensors each each grant to the Licensor a worldwide, irrevocable, non-exclusive license to for any and all purposes.
License Property
The Kaminski Patent Family shall mean U.S. Patents No. 6,015,542, 6,090,365, 5,595,721, 5,843,398, 6,287,537, and 6,565,827, including associated derivatives.  this includes the ZevalinTM Therapeutic Regimen.  ZevalinTM Kits refer to any kit containing Ibritumomab Tiuxetan for the preparation of Indium-111 Ibritumomab Tiuxetan and Yttrium-90 Ibritumomab Tiuxetan as currently formulated and approved by the FDA.

The Wahl Patent Family shall mean U.S. Patents No. 6,251,362, and 6,022,521, including associated derivatives.

Field of Use
The field of use is all uses.  ZevalinTM Kits relate to the treatment of any B-cells malignancies.

The B-cell lymphomas are types of lymphoma affecting B cells. Lymphomas are 'blood cancers' in the lymph nodes. They develop more frequently in older adults and in immunocompromised individuals. B-cell lymphomas include both Hodgkin's lymphomas and most non-Hodgkin lymphomas.

IPSCIO Record ID: 1370

License Grant
The Company acquired exclusive worldwide rights to the GliaSite® Radiation Therapy System.

Licensor is willing to grant Licensee rights to the Licensor IP in the Territory with a limited field of use of intracavity radiation therapy (brachytherapy) of the brain (“Exclusive Field of Use”).

License Property
the GliaSite® Radiation Therapy System, the only FDA-cleared balloon catheter device used in the treatment of brain cancer.

GliaSite® Radiation Therapy System (RTS) is for the treatment of brain cancer, i.e. primary and recurrent gliomas and metastic brain tumors.  Specifically, the intended use of GliaSite® RTS is the management of surgically resectable brain tumors where adjuvant radiation therapy of the post-resection tissue bed is indicated.

IPSCIO Record ID: 365586

License Grant
Licensee of Israel acquired certain intellectual property for research and development activities relating to the alpha radiation products from the University.
License Property
Alpha radiation products consist of but not limited to the Alpha DaRT technology that is designed to utilize the specific therapeutic properties of alpha particles while aiming to overcome, and even harness for potential benefit, the traditional shortcomings of alpha radiation’s limited range. The Alpha DaRT source is directly inserted into the tumor and is designed to release radiation with a high-linear energy transfer over a range of a few millimeters, potentially sparing the surrounding healthy tissue. It was evaluated that the feasibility, safety and efficacy of the Alpha DaRT technology in a first-in-human study of locally advanced and recurrent squamous cell carcinoma, or SCC, cancers of the skin and head and neck.
Field of Use
Field of use is for treatment of Cancer utilizing radiation therapy.

IPSCIO Record ID: 253950

License Grant
Licensor, an university technology transfer organization, grants a first right of refusal to additional fields not included in the Licensed Field.
License Property
The current patent list includes and refers to Methods and Apparatus for Radiation Therapy, and, Radiation Therapy System with Constrained Rotational Freedom and Radiation Therapy System, and others.

UNITED STATES 5,317,616 METHOD AND APPARATUS FOR RADIATION THERAPY
UNITED STATES 08/071742 RADIATION THERAPY SYSTEM WITH CONSTRAINED ROTATIONAL FREEDOM
UNITED STATES 5,442,675 DYNAMIC COLLIMATOR FOR RADIATION THERAPY
UNITED STATES 5,394,452 VERIFICATION SYSTEM FOR RADIATION THERAPY
UNITED STATES 5,528,650 METHOD AND APPARATUS FOR RADIATION THERAPY
UNITED STATES 5,647,663 RADIATION TREATMENT PLANNING METHOD AND APPARATUS

Therapy Unit shall mean any item or unit capable on its own of producing radiation for the purposes of diagnostics, imaging, or therapy and that employs or is produced by the practice of an invention claimed in the Licensed Patents or would otherwise constitute infringement of any claims of the Licensed Patents.

Field of Use
The amendment clarifies that the Licensed Field explicitly excludes medical applications using Ions.

Licensee developed, market and sell advanced and versatile radiation therapy system for the treatment of a wide variety of cancers.

IPSCIO Record ID: 366038

License Grant
Licensee of Israel acquired certain intellectual property for research and development activities relating to the alpha radiation products from the Israelis University.
License Property
Alpha radiation products consist of but not limited to the Alpha DaRT technology that is designed to utilize the specific therapeutic properties of alpha particles while aiming to overcome, and even harness for potential benefit, the traditional shortcomings of alpha radiation’s limited range. The Alpha DaRT source is directly inserted into the tumor and is designed to release radiation with a high-linear energy transfer over a range of a few millimeters, potentially sparing the surrounding healthy tissue. It was evaluated that the feasibility, safety and efficacy of the Alpha DaRT technology in a first-in-human study of locally advanced and recurrent squamous cell carcinoma, or SCC, cancers of the skin and head and neck.
Field of Use
Field of use is for treatment of Cancer utilizing radiation therapy.

IPSCIO Record ID: 1097

License Grant
Licensee entered into an exclusive license with the University Research Foundation covering certain patented processes which may be used in the manufacture and distribution of a brachytherapy device to be used in the treatment of breast cancer.  The license also allows licensee to sublicense the covered processes for additional fees.
License Property
The ClearPath device is placed through a single incision and is designed to conform to the resection cavity, allowing for more conformal therapeutic radiation dose distribution following lumpectomy compared to other methods of APBI. ClearPath is designed to accommodate either high-dose, ClearPath-HDR, or low-dose rate, ClearPath-CR, treatment methods. Brachytherapy, or internal radiation therapy, makes use of radioactive sources or seeds and has emerged as one of the most common treatments of prostate cancer.
Field of Use
The rights granted apply to the medical industry relating to cancer treatments.
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