Description
Category: Technology Licenses
Created On: 2022-04-28
Record Count: 4
Primary Industries
- Drugs
- Cancer
- Diagnostic
- Disease
- Therapeutic
- Pharmaceuticals
- Drug Discovery
IPSCIO Report Record List
Below you will find the records curated into this collection. This summary includes the complete licensed property description so that you can review and determine if this collection covers the topics, technology or transaction type that is relevant for your needs. The full report will include all relevant deal data such as the royalty base, agreement date, term description, royalty rates and other deal terms. For reference, here is a sample of a full IPSCIO curated royalty rate report: Sample Report
IPSCIO Record ID: 28093
IPSCIO Record ID: 249348
Hsp90 Diagnostic means a product or service for determining a person that is susceptible to treatment with a Hsp90 Therapeutic and/or monitoring such treatment and/or providing a prognosis of such treatment, in each case such treatment being for the purpose of treating and/or preventing a disease, disorder or condition.
Hsp90 Therapeutic means one or more molecules that primarily (i.e. the most potent activity) target and modulate one or more of Heat Shock Protein 90 (Hsp90) [and/or cochaperones of Heat Shock Protein 90 ( e.g. Hip and Hop), but not client proteins of Heat Shock Protein 90 such as c-Kit and EGFR,] and compositions that contain such a molecule(s). For the avoidance of doubt, the chemical entities disclosed and/or claimed in the Patent Rights indicated in Exhibit Y and IPI 504 are included as Hsp90 Therapeutics.
Hedgehog Diagnostic means a product or service for determining a person that is susceptible to treatment with a Hedgehog Therapeutic and/or monitoring such treatment and/or providing a prognosis of such treatment, in each case such treatment being for the purpose of treating and/or preventing a disease, disorder or condition.
Hedgehog Therapeutic means one or more molecules that primarily target (i.e. the most potent activity) and modulate one or more member(s) of the Hedgehog pathway and compositions that contain such a molecule(s). For the avoidance of doubt, the chemical entities disclosed and/or claimed in the Patent Rights [, and IPI 609, the IPI 609 polymorph, and reduced A-ring analogs of IPI 609] are included as Hedgehog Therapeutics.
The Licensee Patents are for Analogs ofBenzoquinone-Containing Ansamycins and Methods of Use Thereof, and, Ansamycin Formulations and Methods of use Thereof, and, Methods of Treatment Using Hydroquinone Ansamycins, and, Crystal Form, and, Cyclopamine Analogs and Methods of Use Thereof , and, Dosing Regimens for the Treatment of Cancer, and, Methods for Synthesizing Cyclopamine Analogs.
IPSCIO Record ID: 243475
Project means Hedgehog Project and/or Hsp90 Project.
Hsp90 Diagnostic means a product or service for determining a person that is susceptible to treatment with a Hsp90 Therapeutic and/or monitoring such treatment and/or providing a prognosis of such treatment, in each case such treatment being for the purpose of treating and/or preventing a disease, disorder or condition.
Hsp90 Therapeutic means one or more molecules that primarily (i.e. the most potent activity) target and modulate one or more of Heat Shock Protein 90 (Hsp90) [and/or cochaperones of Heat Shock Protein 90 ( e.g. Hip and Hop), but not client proteins of Heat Shock Protein 90 such as c-Kit and EGFR,] and compositions that contain such a molecule(s). For the avoidance of doubt, the chemical entities disclosed and/or claimed in the Patent Rights indicated in Exhibit Y and IPI 504 are included as Hsp90 Therapeutics.
Hedgehog Diagnostic means a product or service for determining a person that is susceptible to treatment with a Hedgehog Therapeutic and/or monitoring such treatment and/or providing a prognosis of such treatment, in each case such treatment being for the purpose of treating and/or preventing a disease, disorder or condition.
Hedgehog Therapeutic means one or more molecules that primarily target (i.e. the most potent activity) and modulate one or more member(s) of the Hedgehog pathway and compositions that contain such a molecule(s). For the avoidance of doubt, the chemical entities disclosed and/or claimed in the Patent Rights [, and IPI 609, the IPI 609 polymorph, and reduced A-ring analogs of IPI 609] are included as Hedgehog Therapeutics.
The Licensor Patents are for Analogs ofBenzoquinone-Containing Ansamycins and Methods of Use Thereof, and, Ansamycin Formulations and Methods of use Thereof, and, Methods of Treatment Using Hydroquinone Ansamycins, and, Crystal Form, and, Cyclopamine Analogs and Methods of Use Thereof , and, Dosing Regimens for the Treatment of Cancer, and, Methods for Synthesizing Cyclopamine Analogs.
“Indication†means a type of cancer (tumor type) or a disease, disorder or a condition other than a type of cancer.
IPSCIO Record ID: 372553
Compound shall mean x-305, any prodrug or metabolite of x-305, any isomer, ester, salt, hydrate, solvate, or polymorph of x-305, including any Backup Compound.
Backup Compounds shall mean all Hsp90 Inhibitors claimed in the Patent Cooperation Treaty application of publication number WO 2008/115719, as well as their prodrugs and metabolites, and all isomers, esters, salts, hydrates, solvates, and polymorphs thereof.
The Patents are for x-305 or Hsp90 inhibition, meaning a compound that binds to, and selectively and specifically inhibits, Hsp90.
An Hsp90 inhibitor is a substance that inhibits that activity of the Hsp90 heat shock protein. Since Hsp90 stabilizes a variety of proteins required for survival of cancer cells, these substances may have therapeutic benefit in the treatment of various types of malignancies.
