Royalty Report: Medical, Cancer, Diagnostic – Collection: 26489

$150.00

Curated Royalty Rate Report
Category: Technology Licenses, Created On: 2022-04-28, Record Count: 10

Description

This collection of transactions and supporting information was developed using our AI algorithm to curate similar royalty reports into a cohesive collection to support your licensing, transfer pricing or other transaction scenarios where documented royalty rates and/or deal terms are important.
Category: Technology Licenses
Created On: 2022-04-28
Record Count: 10

Primary Industries

  • Medical
  • Cancer
  • Diagnostic
  • Device
  • Therapeutic
  • Scientific & Technical Instruments
  • Disease
  • Dental
  • Drug Discovery
  • Drugs

IPSCIO Report Record List

Below you will find the records curated into this collection.  This summary includes the complete licensed property description so that you can review and determine if this collection covers the topics, technology or transaction type that is relevant for your needs.  The full report will include all relevant deal data such as the royalty base, agreement date, term description, royalty rates and other deal terms.  For reference, here is a sample of a full IPSCIO curated royalty rate report: Sample Report

IPSCIO Record ID: 26489

License Grant
The Company hereby grants to Licensee an exclusive, worldwide, royalty-bearing, limited license under the Licensed Technology to make, have made, import, use, sell and have sold the Devices solely within the Field of Use.
License Property
U.S. 5,860,934                    Method and Device for Mechanical Imaging of Breast         Issued 01/19/99

(CIP of App. 07/994,109)

U.S. 5,833,633                    Device for Breast Haptic Examination                       Filed 11/03/97

(CIP of 5,524,636)                                                                           Issued 11/10/98

U.S. 5,785,633                    Method and Device for Mechanical Imaging of Prostate       Filed 02/27/96

(CIP of 5,524,636)                                                                           Issued 07/28/98

U.S. 5,836,894                    Apparatus for Measuring Mechanical Parameters of the       Filed 06/10/97

(CIP of 5,524,636)                Prostate and for Imaging the Prostate Using such           Issued 11/17/98

U.S. 5,922,018                    Method for Using a Transrectal Probe to Mechanically        Filed 06/10/97

(CIP of 5,524,636)                Image the Prostate Gland                                    Issued 07/13/99

U.S. 5,524,636                    Method and Apparatus for Elasticity Imaging                Filed 12/21/92

U.S. 5,265,612                    Intracavity Ultrasonic Device for Elasticity Imaging       Filed 12/21/92

U.S. 6,142,959                    Device for Palpation and Mechanical Imaging of the         Filed 07/22/99

                                  Prostate                                                   Issued 11/07/00

PCT/US00/19756                    Device for Palpation and Mechanical Imaging of the         Filed 07/21/00

                                  Prostate

U.S. 09/843,056                   Apparatus and Method for Mechanical Imaging of Breast      Filed 04/26/01

PCT/US01/13551                    Apparatus and Method for Mechanical Imaging of Breast      Filed 4/26/01

U.S. 60/200,433                   Apparatus and Method for Mechanical Imaging of Breast      Filed 4/28/00

U.S. 09/819,419                   Real Time Mechanical Imaging of the Prostate               Filed 03/28/01

Field of Use
Field of Use shall mean the diagnosis of and the treatment of (a) benign prostatic hyperplasia; (b) prostatitis; © prostate cancer; or (d) any other conditions of or disorders of the prostate, whether healthy or diseased, and any other condition of urologic disorder which may be diagnosed, imaged or treated using any diagnostic or imaging process.  Prostate imaging system and related patented technology.

IPSCIO Record ID: 6210

License Grant
The Licensor hereby grants to the Licensee an exclusive, worldwide, sublicensable license to the Licensor's Patents and the Licensor's Trade Secrets to (i) make, have made, use, market, offer for sale, sell, have sold, distribute, have distributed, import, have imported and otherwise exploit Products in the Field of Use, and (ii) practice methods covered by the Licensor's Patents and the Licensor's Trade Secrets to make, have made, use, market, offer for sale, sell, have sold, distribute, have distributed, import, have imported and otherwise exploit Products in the Field of Use.
License Property
The Licensor  has developed expertise and intellectual property in the area of a prostate mechanical imaging system (the “PMI Systems”).

“Field of Use” means diagnosis or treatment of urologic disorders of the prostate, kidney or liver.

a. Method and Device for Real Time Mechanical Imaging of Prostate, USA Patent Application No 11/123,999, Filing Date May 6, 2005.

b. Method and Dual-Array Transducer Probe for Real Time Mechanical Imaging of Prostate, USA Patent Application No 11/146,367, Filing Date June 6, 2005.

c. Prostate Mechanical Imaging probe, USA Patent Application No 29/320,480, Filing Date June 27, 2008.

d. Calibration chamber for Prostate Mechanical Imaging probe, USA Patent Application No 29/320.474, Filing Date June 27, 2008.

IPSCIO Record ID: 5639

License Grant
The Licensor granted the Licensee an exclusive, worldwide, royalty-bearing, limited license under the Licensed Technology to make, have made, import, use, sell and have sold the Devices solely within the Field of Use.
License Property
The Licensor’s technology allows the user to direct microwave energy emitted at the end of a catheter in a specific direction, which is believed to be a distinct advantage in the possible treatment of prostate disease.

09/248,165     A medical instrument for providing/withdrawing heat from a target
09/248,168    A medical instrument having a collinear      
09/248,170    Relates to a unique antenna structure        
09/377,458    Heat Pipe Array  An array of antennas for providing increased uniformity of radiated microwave energy into a tissue mass
6,181,970        Microwave devices used in medical hyperthermia and thermotherapy

Field of Use
Field of Use shall mean the treatment of (a) benign prostatic hyperplasia; (b) prostatitis; (c) prostate cancer; or (d) any other conditions of urologic disorder which may be diagnosed, imaged or treated using a catheter-based microwave technology or sensor imaging systems.  Technology, know-how, and patents related to urologic disorders that may be detected or treated using a catheter-based microwave technology.

IPSCIO Record ID: 6023

License Grant
The Licensor has granted the Licensee a non-exclusive worldwide license to use certain medical imaging technologies, known as Optical Coherence Tomography, or ‘OCT,’ in the field of general dentistry, excluding oral surgery and imaging through a microscope.
License Property
(a) Licensee’s Release of a Licensed Product;
(b) Licensee’s First Commercial Sale of a Licensed Product; or
(c) the second anniversary of the effective date.

Optical Coherence Tomography is a technique for obtaining sub-surface images of translucent or opaque materials at a resolution equivalent to a low-power microscope. It is effectively ‘optical ultrasound’, imaging reflections from within tissue to provide cross-sectional images.

There are many industrial, medical, and other applications where high resolution (generally less than 10 micrometer) images of, and measurements of distances, thicknesses, and optical properties of, a biological or other sample are required.

“Method And Apparatus For Optical Imaging With Means For Controlling The Longitudinal Range Of The Sample”  Issued US Patent 5,321,501, June 14, 1994. Filed 4/29/92. – A method and apparatus for performing optical imaging on a sample wherein longitudinal scanning or positioning in the sample is provided by either varying relative optical path lengths for an optical path leading to the sample and to a reference reflector, or by varying an optical characteristic of the output from an optical source applied to the apparatus. Transverse scanning in one or two dimensions is provided on the sample by providing controlled relative movement between the sample and a probe module in such direction and/or by steering optical radiation in the probe module to a selected transverse position. The probe module may be an external module or may be an endoscope or angioscope utilized for scanning internal channels. Multiple optical paths may be provided for parallel scanning and focus may be enhanced by varying the focal point in the sample in synchronism with longitudinal scanning of the sample.

“Method and Apparatus for Performing Optical Measurements” Issued US Patent 5,459,570, Oct. 14, 1995. Filed 3/16/93.

“Method and Apparatus for Performing Optical Imaging and Measurements” Issued in Europe and Japan.

“Method and Apparatus for Acquiring Images using a CCD Detector Array and No Transverse Scanner” Issued US Patent 5,465,147, Nov. 7, 1995. Filed 6/2/94. CIP of 4/29/91 filing.

“Method and Apparatus for Performing Optical Measurements using a Fiber Optic Imaging Guidewire, Catheter or Endoscope” Issued US Patent 6,134,003, Oct. 17, 2000. Filed 2/27/96.

“Methods and Apparatus for Forward-Directed Optical Scanning Instruments for the Acquisition of Optical Imaging and Delivery of Optical Radiation,” Pending Patent.

“Grating Based Phase Control Optical Delay Line” Issued US Patent 6,111,645 August, 2000.

“Method and Apparatus for Performing Optical Measurements using a Rapidly Frequency Tuned Laser” Issued US Patent 5,956,355 September 21, 1999.

“Short Coherence Length, Doppler Velocimetry System” Issued US Patent 5,501,226, 3/26/96. Filed 10/16/94. Issued EPO and Japan.

“Short Coherence Length, Doppler Velocimetry System” Issued US Patent 5,549,114, 8/27/96. Filed 10/23/95. Issued EPO and Japan.

“Optical Coherence Tomography Assisted Surgical Apparatus” Issued US Patent 6,004,314 December 21, 1999.

“OCT-Assisted Surgical Microscope with Multi- Coordinate Manipulator” Issued US Patent 5,795,295.

“Optical Coherence Tomography with New Interferometer” Issued US Patent 6,053,613.

“Method and Apparatus for Simultaneous Measuring the Length and Refractive Error of and Eye” Issued US Patent 5,975,699.

Measurement of Lens Characteristics” Issued US Patent 5,469,261 11/21/95.

“Fundus Illumination Apparatus Formed from Three Separated Radiation Path Systems” Issued US Patent 5,506,634, 4/9/96.

“Optical Coherence Tomography Corneal Mapping Apparatus” Issued US Patent 5,491,524, 2/13/96. Filed 10/5/94.

“Method and Apparatus for Optical Coherence Tomographic Fundus Imaging” Pending Patent.

“Gaze Tracking using Optical Coherence Tomography” Issued US Patent 5,644,642, 7/1/97. Filed 4/3/95.

“Optical Coherence Tomography Assisted Ophthalmologic Surgical Microscope” Issued US Patent 5,493,109, 2/20/96. Filed 8/18/94.

“Method and Apparatus for Optical Coherence Tomographic Fundus Imaging without Vignetting” Issued US Patent 5,537,162, 6/16/96. Filed 12/17/93.

“Method and Apparatus for High Speed Longitudinal Scanning in Imaging Systems” Issued US Patent 6,191,862 2/20/01.

“Fiber Optic Needle Probes for Optical Coherence Tomography Imaging” Patent Pending.

“Micro-Lens for Miniature Optical Probes” Patent Pending.

“Method and Apparatus for Performing Optical Frequency Domain Reflectometry” Issued US Patent 6,160,826. 12/12/00. Filed 1999.

“Broadband Light Source System and Method Thereof” Patent Pending.

“Apparatus and Method for Selective Data Collection and Signal to Noise Ratio Enhancement Using Optical Coherence Tomography” Patent Pending Filed 4/6/01.

“Fiber Optic Endoscopic Gastrointestinal Probe” Patent Pending.

IPSCIO Record ID: 27570

License Grant
Licensor, a wholly owned subsidiary of the Licensee, hereby grants and agrees to grant to Licensee a license, with the right to grant sublicenses, to use the Licensed Patent Rights, the Licensed Copyrights, the Licensed Technology, and the Licensed Trademarks, to make, have made, use and sell, during the term of this Agreement, Products employing the Licensed Intellectual Property.

The License Agreement grants the Licensee the exclusive right to distribute the BreastCare DTS™ in the United States, Canada and certain countries in Asia, including China. Rights granted include the right to grant sublicenses, to use the Licensed Patent Rights, the Licensed Copyrights, the Licensed Technology, and the Licensed Trademarks, to make, have made, use and sell, during the term of this Agreement, Products employing the Licensed Intellectual Property. The license granted is limited to the United States, Canada, Asia and, subject to Licensor’s Right of First Refusal, the Open Territory and is exclusive within the United States, Canada and Asia as to all parties including the Licensor and non-exclusive as to the Open Territory except to the extent that Licensor does not exercise its Right of First Refusal. The Licensor hereby grants to Licensee the exclusive right to use the trademarks as set forth within the Exclusive Territory, the non-exclusive right to use the trademarks as set forth in the Open Territory, subject to Licensor’s Right of First Refusal, and the non-exclusive right to use the trademarks set forth within the Exclusive Territory and, subject to Licensor’s Right of First Refusal, the Open Territory.

License Property
Licensor owns or controls certain proprietary rights, including, but not limited to, patents, trademarks, copyrights, United States Food and Drug Administration ('FDA') filings, clinical studies, data, techniques, trade secrets, contract rights, concepts and know-how, relating to a product referred to as BreastCare DTS™ referred to herein as the “Product.” The Product has been cleared by the FDA to be marketed as an adjunct to mammography and other procedures for the detection of breast disease, including breast cancer. Licensor also owns or controls or has contracted to obtain the benefits of certain apparatus and methods for making the Product.

The BreastCare DTSâ„¢ measures underlying breast tissue temperature and not skin surface temperature by retaining the emitted heat when BreastCareâ„¢ DTS is placed against the breast for 15 minutes. The averaged and recorded reading on the BreastCare DTSâ„¢ has taken into consideration that the temperature patterns of a woman's breasts are closely symmetrical. This method detects abnormalities by comparing the temperature differences in the corresponding areas of a woman's breasts.

The licensed technology includes the BreastCare DTSâ„¢.  It is patented, non-invasive and FDA-cleared as an adjunct to mammography and other established procedures for the detection of breast disease, including breast cancer. DTS stands for “Differential Temperature Sensor,” indicating the ability of the device to compare temperatures in one area of the breast with others in the same breast and the other breast. The BreastCare DTSâ„¢device consists of two mirror image, lightweight and disposable foam pads with three wafer-thin foil sensors on each pad. Each of the three segments on each pad contains 18 rows of heat-sensitive chemical dots. The device is easy to use and requires no electricity or probes. The test is completely non-invasive. The pads are easily placed on a woman’s breasts inside the bra for 15 minutes. The device measures the deep heat energy that is transferred to the surface of the skin. Each heat-sensitive dot is calibrated to record the temperature of the surface of the breast. The dots themselves change color from blue to pink when exposed to specific temperatures. The results are clearly displayed and can be immediately evaluated. The heat-sensitive dots have embedded memory, which allows the results to be read after each test is completed.

U.S. Patent 6,086,247 as well as all related applications and/or issued patents. Related applications includes any related foreign or U.S. issued or pending applications, continuation applications, continuation-in-part applications, divisional applications, reissue applications, and provisional application.
U.S. Patent 6135968 – Differential temperature measuring device and method; Prostate Screening Device.
RE 32,000
RE 4,624264
Patent 4651749

Trademarks
BreastCare DTSTM BreastAlertTM Differential Temperature Sensor

Field of Use
The grant provides the right to develop, manufacture and commercialize the Product and derivative products for, among other purposes, the detection of disease, including breast cancer.  The Products covered by the License shall include any temperature sensing product manufactured by or on behalf of the Licensor using the patented technology or improvements thereto.

IPSCIO Record ID: 26135

License Grant
Licensor hereby grants to Licensee of Hong Kong for the Term for the Patented Licensed Technology the exclusive (even as to Licensor), sublicensable, royalty-bearing right and license to make, have made, use, import, offer for sale, and sell devices, sensors and other products or services incorporating the Patented Licensed Technology and Improvements in the Territory.
License Property
Licensor is the sole owner and holder of all intellectual property, proprietary rights and know-how, and all other rights and interests related to and associated with the Biofield Breast Cancer Technology and the Patented and Unpatented Licensed Technology.

The Licensor's Diagnostic System is a breast cancer diagnostic device, which employs single-use sensors to measure and analyze changes in cellular electrical charge distributions associated with the development of epithelial cancers, such as breast, ovaries, skin, prostate, and colon cancers. The company's device is intended for palpable breast lesions, in women under 55 years of age.

PATENTS

Expiry

US Appli.#
DESCRIPTION
COUNTRY
Date
Year

5217014
Depolarized Pre-Gelled Electrodes
U.S.
6/8/2010
6/8/1993

4955383
Discriminant Function Analysis Method & Apparatus For
U.S.
9/11/2007
9/11/1990

Disease Diagnosis & Screening – Device 1

5320101
Discriminant Function Analysis Method & Apparatus For
U.S.
6/14/2011
6/21/1994

Disease Diagnosis & Screening With Biopsy Needle Sensor

5415164
Apparatus & Method For Screening & Diagnosing Trauma
U.S.
5/16/2012
5/16/1995

or Disease in Body Tissues

5660177
D.C. Biopotential Sensing Electrode Assemblies For
U.S.
10/17/2014
8/26/1997

Apparatus For Disease, Injury & Bodily Condition

Screening or Sensing.

5427098
Noninvasive Method For Determining Treatment Based
U.S.
3/14/2014
6/27/1995

Upon Lesion Cell Proliferation

374184
D.C. Biopotential Measuring Unit
U.S.
10/1/2010
10/1/1996

5678547
Method & Apparatus For Screening or Sensing Bodily
U.S.
4/26/2015
10/21/1997

Conditions Using DC Biopotentials

APPL
DC BIOPOTENTIAL ELECTRODE CONNECTOR &

issued-us5,895,298
CONNECTOR CONDITION SENSOR
U.S.
5/29/2017
4/20/1999

5697369
Method & Apparatus For Disease, Injury & Bodily Condition
U.S.
12/22/2008
12/16/1997

Sensing

(Response re restrict appl. To 1 invention)

10/31/1999

6351666
Method & Apparatus For Sensing & Processing

Biopotentials

(Filing, claims & assignment fees)
U.S.

9/30/1999

(Formal drawings to Patent Office)

10/31/1999

Field of Use
The rights granted apply to the breast cancer field.

IPSCIO Record ID: 383615

License Grant
The University grants the right and worldwide, non-exclusive license, with the right to grant sublicenses, in the Field to make, have made, use, sell, offer for sale, and import the Licensed Technology and to practice under the Patent Rights to the end of the term.
License Property
University is the joint owner by assignment with Carnegie Mellon University of certain Patent Rights,

The Patent Rights are titled A Method and Apparatus for Holding Cells.

Field of Use
The Field shall mean human and veterinary cellular imaging in the Cancer Diagnostics Field and the Drug Development Field.

The Cancer Diagnostics Field shall mean diagnostic assays to detem1ine therapeutic efficacy of then-available chemotherapeutics or biologics on cancer or screening assays for the detection of cancer.

The Drug Development Field shall mean research conducted to measure the effect of preclinical, clinical or commercial stage cancer agents on primary or early passage cell strains.

IPSCIO Record ID: 238982

License Grant
University hereby grants to Licensee an exclusive, worldwide right and license, with the right to grant Sublicenses and to permit Sub-sublicenses to practice under and use the Licensed Patents and the Licensed Technology to make, have made, use, market, sell, have sold, import, distribute, and offer for sale any Licensed Product, Licensed Process or Generic Product. University hereby agrees, subject to the terms and conditions herein contained, that the term 'exclusive' means that University shall not grant any other license to any third party or take any action inconsistent with the rights granted to Licensee under this Agreement relating to the Licensed Patents or Licensed Technology.
License Property
Licensed Patents shall mean
6,265,448 – Method for chemoprevention of prostate cancer
6,413,533 – Method for chemoprevention of prostate cancer
6,413,534 – Method for chemoprevention of prostate cancer
6,410,043 – Method for chemoprevention of prostate cancer
6,413,535 – Method for chemoprevention of prostate cancer

Licensed Technology shall mean any technology, trade secrets, methods, processes, know-how, show-how, data, information, or results relating to the patent applications, developed by the Contributors and owned by University, including the chemoprevention of prostate cancer and, more particularly, to a method of administering to a subject an effective dose of a chemopreventive agent or pharmaceutical preparation comprising an anti-estrogen or SERM, including, toremifene and analogs or metabolites thereof, to prevent recurrence of, suppress or inhibit prostate carcinogenesis.

Field of Use
Patents relate to toremifene for the reduction in the incidence of prostate cancer in men with high grade PIN and its composition of matter and method of use patents and patent applications relating to Andarine to market, distribute and sell licensed products.

IPSCIO Record ID: 6147

License Grant
The Licensor, a university foundation, granted the Licensee the worldwide right and license, to use the Licensed Technology for the non-invasive measurement of carotenoids and similar or related compounds in human skin including related research and to the extent not prohibited by other patents to practice the licensed processes, until the expiration of the last to expire of any of Licensor's rights in the technology and the right to sublicense the same.
License Property
The Licensor's technology relates to Case No. U-2612, entitled Noninvasive Detection and Mapping of Chemical Substances in the Skin and Skin Related Malignancies and Case No. U-2970, entitled Method and System for Raman Chemical Imaging of Carotenoids and Related Compounds in Living Human Tissue for use in the sale of dietary supplements (the “Dietary Supplement License”.

A method and apparatus are provided for the determination of levels of carotenoids and similar chemical compounds in biological tissue such as living skin (34). The method and apparatus provide a noninvasive, rapid, accurate, and safe determination of carotenoid levels which in turn can provide diagnostic information regarding cancer risk, or can be a marker for conditions where carotenoids or other antioxidant compounds may provide diagnostic information.  The method and apparatus utilize the technique of resonance Raman spectroscopy to measure the levels of carotenoids and similar substances in tissue. In this technique, laser light is directed upon the area of tissue which is of interest. A small fraction of the scattered light is scattered inelastically, producing the carotenoid Raman signal which is at a different frequency than the incident laser light, and the Raman signal is collected, filtered, and measured. The resulting Raman signal can be analyzed such that the background fluorescence signal is subtracted and the results displayed and compared with known calibration standards.

Field of Use
Field of Use shall mean the use of the Licensed Technology for the non-invasive measurement of carotenoids and similar or related compounds in human skin including related research; however, the above Field of Use does not include the use of the technology for identifying, imaging, locating, and/or diagnosing skin lesions or skin malignancies in human patients. The above Field of Use does not include veterinary applications; however, it is agreed that Licensee may use laboratory, in vitro, and in vivo animal model methods to research, develop and validate Licensed Products and Licensed Processes. For avoidance of doubt, human skin is defined as the continuous external membrane (integument) enveloping the body and consisting of the epidermis and dermis, hair, nails, sebaceous glands, sweat glands, and mammary glands; the skin does not include mucosal tissue such as the lining of the mouth.

IPSCIO Record ID: 7324

License Grant
In this related party cross-license agreement the Company granted an exclusive license to use the Company’s technology for certain applications.

In return, the Licensee granted the Company an exclusive license to use Licensee's technology for certain applications.

License Property
TUNA® (transurethral needle ablation) system treats benign prostatic hyperplasia (BPH), a non-cancerous condition also known as “enlarged prostate.”

The TUNA System is designed to offer a minimally invasive alternative for the treatment of benign prostatic hyperplasia by selectively shrinking the hyperplastic tissue that compresses the urethra limiting urinary flow.

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