Royalty Report: Medical, Device, Surgical – Collection: 2016

License Grant

The Company hereby grants to Licensee a worldwide, royalty-bearing, and exclusive license under the Subject Technology to make, have made, use, import, sell and offer for sale Licensed Products technology related to a percutaneous filter for carotid angioplasty (U.S.  Patent No. 5,695,519).

The Company is developing a percutaneous temporary filter that is mounted on a guide wire and is used to prevent stroke-causing blood clots from reaching various organs of the human body.

The filter is deployed remotely, opened within a vessel and then remotely closed, safely and reliably removed with clots intact within a mesh filter containing the entrapped material.  The size of the filter is such that blood flow is not significantly reduced through straining, but embolytic debris is caught and retained by the filter.

License Property

Subject Technology
1. U.S. Patent Number 5,695,519;
2. [Patent applications for percutaneous filters for carotid angioplasty and any patents arising out of such patent applications]

License Grant

The Inventor, an individual, hereby sells, transfers, assigns, conveys, sets over, grants and delivers to Buyer, the Existing Technology and all of the Inventors worldwide rights, title and interest in and to the Existing Technology for whatever purpose or purposes Buyer shall, in its sole discretion, determine, including, without limitation, the exclusive right to make, use, or sell products utilizing the Existing Technology, and also including any and all prototypes, components, patents, patent infringement claims, trademarks and trade-names relating to the Existing Technology, all to the end that Buyer, by virtue of such purchase, shall be the sole owner of the Existing Technology.

License Property

Inventor has designed, invented and produced an experimental model of a nitinol blood clot filter.

'Patent' means that U.S. patent #4,425,908—— nitinol blood clot filter (the 'Filter').

Field of Use

The agreement is for the medical industry.

License Grant

University is willing to grant a worldwide, exclusive license in the defined FIELD OF USE to Licensee.  The University is the owner and that it has the right to exclusively license those inventions which are the subject matter of USC File No. 2651 entitled 'Balloon Protection Guide Wire Device For Carotid Balloon Angioplasty and Stenting' and USC Pile 2639 entitled 'New Balloon-Inflated Carotid Artery Stent to Assist in Carotid Artery Balloon Angioplasty'.

License Property

Guardian Embolization Protection System patented technology with primary use in the neurointerventional and cardiology markets these markets focus on arteries and veins leading to the brain and those in the heart, and the removal of blockages in these veins and arteries.  The device is designed to prevent deadly embolisms during surgery to clear blocked arteries and prevent strokes and heart attacks.  The key to this device, known as the Guardian System, is a thin string of wire, really a metal tube not much larger in diameter than a human hair, with a marble-sized balloon attached toward the end.

USC File 2651 U.S. Patent Application Serial No. 08/767,221 filed December 16, 1996 (abandoned) entitled 'Cerebral Protection Balloon For Use In Carotid Artery Angioplasty and Stenting'

USC File 2561 U.S. Patent Application Serial No. 08/906,890 filed August 6,1997 (which is a continuation of U.S. Ser. No. 08/767,221), entitled Angioplasty Catheter'.

USC File 2561 PCT Patent Application Serial No. PCT/US97/23257 filed December16, 1997 and corresponding to U.S. Patent Applications Serial Nos. 08/767,221and 08/906,890.

USC File 2639 Invention Disclosure entitled 'New Balloon-Inflated Carotid Artery Stent to Assist in Carotid Artery Balloon Angioplasty'.

Field of Use

'FIELD OF USE' shall mean diagnostic and/or therapeutic devices to be used in the treatment or management of patients via the carotid artery or other arteries or veins.

License Grant

Licensor, a nonprofit academic medical center, hereby grants to Licensee for the Term an exclusive, worldwide license to use the Licensed Technology in the Field of Use to (i) make, have made, develop, use, import, export, distribute, market, promote, offer for sale, and sell Products in the Field of Use, and (ii) practice in the Field of Use any method, process or procedure claimed within the Licensed Technology.

License Property

Licensed Patents
– U.S. Utility Application No.11/700,987, Filed 2/1/2007, “A METHOD AND APPARATUS FOR INCREASING BLOOD FLOW THROUGH AN OBSTRUCTED BLOOD VESSEL”, Henry Woo, MD, David Fiorella, MD, PhD. Publication Number US 20070208361 A1.

– U.S. Application No.60/764,206, Filed 2/1/2006, “A METHOD AND APPARATUS FOR INCREASING BLOOD FLOW THROUGH AN OBSTRUCTED BLOOD VESSEL”, Henry Woo, MD, David Fiorella, MD, PhD. Expired.

-U.S. Application No.60/793,588, Filed 4/20/2006, “A METHOD AND APPARATUS FOR INCREASING BLOOD FLOW THROUGH AN OBSTRUCTED BLOOD VESSEL”, Henry Woo, MD, David Fiorella, MD, PhD. Expired.

Field of Use

The license relates to its revascularization technology for the treatment of ischemic stroke.

Ischemic stroke occurs when a blood clot blocks or narrows an artery leading to the brain. A blood clot often forms in arteries damaged by the buildup of plaques (atherosclerosis). It can occur in the carotid artery of the neck as well as other arteries. This is the most common type of stroke.